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Rab4a Gene Detail
Summary
  • Symbol
    Rab4a
  • Name
    RAB4A, member RAS oncogene family
  • Synonyms
    Rab4
  • Feature Type
    protein coding gene
  • IDs
    MGI:105069
    NCBI Gene: 19341
  • Gene Overview
    MyGene.info: RAB4A
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:123805985-123835287 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 72.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    267 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105069
protein coding gene Chr8:123805846-123835291 (.)
129S1/SvImJ MGP_129S1SvImJ_G0034261
protein coding gene Chr8:127440943-127469528 (+)
A/J MGP_AJ_G0034241
protein coding gene Chr8:122186000-122216047 (+)
AKR/J MGP_AKRJ_G0034168
protein coding gene Chr8:125696820-125726119 (+)
BALB/cJ MGP_BALBcJ_G0034234
protein coding gene Chr8:122372962-122402379 (+)
C3H/HeJ MGP_C3HHeJ_G0033945
protein coding gene Chr8:126335390-126364498 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034754
protein coding gene Chr8:131717714-131747958 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031696
protein coding gene Chr8:114965115-114993530 (+)
CAST/EiJ MGP_CASTEiJ_G0033273
protein coding gene Chr8:126443808-126476259 (+)
CBA/J MGP_CBAJ_G0033918
protein coding gene Chr8:136532701-136565488 (+)
DBA/2J MGP_DBA2J_G0034074
protein coding gene Chr8:121337803-121369413 (+)
FVB/NJ MGP_FVBNJ_G0034018
protein coding gene Chr8:120501971-120531444 (+)
LP/J MGP_LPJ_G0034164
protein coding gene Chr8:127603390-127631952 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034065
protein coding gene Chr8:138674041-138704048 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034773
protein coding gene Chr8:125926853-125960449 (+)
PWK/PhJ MGP_PWKPhJ_G0032974
protein coding gene Chr8:121094187-121124306 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032814
protein coding gene Chr8:124573989-124604826 (+)
WSB/EiJ MGP_WSBEiJ_G0033389
protein coding gene Chr8:126655587-126688089 (+)



Homology
more
  • Human Ortholog
    RAB4A, RAB4A, member RAS oncogene family
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAB4A, RAB4A, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HRES1, HRES-1, HRES-1/RAB4, RAB4
  • Links
    NCBI Gene ID: 5867
    neXtProt AC: NX_P20338
    UniProt: P20338

  • Chr Location
    1q42.13; chr1:229271062-229305894 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019478 Ensembl Gene Model | MGI Sequence Detail 29303 C57BL/6J ±  kb
transcript ENSMUST00000118535 Ensembl | MGI Sequence Detail 1419 Not Applicable  
polypeptide ENSMUSP00000113886 Ensembl | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 58

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-32108, MGI:2142629
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
  • Latest
    J:241068 Lucitti JL, et al., Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016 Dec;47(12):3022-3031

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory