Rab4a
Gene Detail

Symbol Name ID

Rab4a RAB4A, member RAS oncogene family MGI:105069

Synonyms

Rab4

Feature Type

protein coding gene

Genetic Map

Chromosome 8

72.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:123805985-123835287 bp, + strand From VEGA annotation of GRCm38   29303 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:101538  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab4a

Human homologs

Human Homolog		RAB4A, RAB4A, member RAS oncogene family
NCBI Gene ID		5867
neXtProt AC		NX_P20338
Human Synonyms		HRES-1/RAB4, RAB4
Human Chr (Location)		1q42-q43; chr1:229406879-229440518 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (28 annotations)

Process	GTP catabolic process, positive regulation of ATPase activity, ...
Component	cytoplasm, cytosol, ...
Function	ATPase activator activity, ATPase binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (29)    Tissues (6)    Images (15)
Theiler Stages: 23

Assay Type	Results
RNA in situ	29

cDNA source data(58)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(59) cDNA(59)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000030744 (Evidence)
Ensembl Gene Model	ENSMUSG00000019478 (Evidence)
Entrez Gene	19341 (Evidence)
UniGene	9221
DFCI	TC1580726, TC1603518, TC1674163
DoTS	DT.532528
NIA Mouse Gene Index	U009947
Consensus CDS Project	CCDS52703.1
International Mouse Knockout Project Status	Rab4a

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030744	VEGA Gene Model | MGI Sequence Detail	29303	C57BL/6J
transcript	OTTMUST00000076112	VEGA | MGI Sequence Detail	1080	Not Applicable
polypeptide	OTTMUSP00000040011	VEGA | MGI Sequence Detail	218	Not Applicable

All sequences(32) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(1) : SNPs(167 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013631	ras-related protein Rab-4A

References

(Earliest) J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
(Latest) J:186307 Peng C, et al., Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. J Biol Chem. 2012 Aug 1;
All references(35)

Other accession IDs

MGD-MRK-32108, MGI:2142629