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Cyp2a12
Gene Detail
 Symbol
Name
ID
Cyp2a12
cytochrome P450, family 2, subfamily a, polypeptide 12
MGI:105055
Feature Type protein coding gene
Genetic Map
Chromosome 7
15.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:27029090-27036807 bp, + strand
From Ensembl annotation of GRCm38

  7718 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69128  Vertebrate Homology Class
2 mouse; 1 rat

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2a12

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2a12 interacts with 32 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 94
RT-PCR 12
cDNA source data(49)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(50) cDNA(49) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000060407 (Evidence)
Entrez Gene13085 (Evidence)
UniGene20770
DFCITC1580820
DoTSDT.492605
EC1.14.14.1
Consensus CDS ProjectCCDS21009.1
International Mouse Knockout Project StatusCyp2a12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060407 Ensembl Gene Model | MGI Sequence Detail 7718 C57BL/6J ±  kb
transcript ENSMUST00000075552 Ensembl | MGI Sequence Detail 1656 Not Applicable 
polypeptide ENSMUSP00000074990 Ensembl | MGI Sequence Detail 492 Not Applicable 

For the selected sequences
All sequences(12) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(124 from dbSNP Build 137)    SNPs within 2kb including multiple locations(140)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008067 Cytochrome P450, E-class, group I, CYP2A-like
Protein Ontology PR:000006219 cytochrome P450 2A12
References (Earliest) J:23304 Iwasaki M, et al., Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction. Biochem J. 1993 Apr 15;291(Pt 2):569-73
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(22)
Other
accession IDs
MGD-MRK-32094

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory