Cyp2a12
Gene Detail

Symbol Name ID

Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 MGI:105055

Feature Type

protein coding gene

Genetic Map

Chromosome 7

15.77 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:27029090-27036807 bp, + strand From Ensembl annotation of GRCm38   7718 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:69128  Vertebrate Homology Class
2 mouse; 1 rat

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2a12

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	aromatase activity, electron carrier activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (106)   
Theiler Stages: 10, 18, 22, 23, 25, 28

Assay Type	Results
RNA in situ	94
RT-PCR	12

cDNA source data(49)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(50) cDNA(49) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000060407 (Evidence)
Entrez Gene	13085 (Evidence)
UniGene	20770
DFCI	TC1580820
DoTS	DT.492605
EC	1.14.14.1
Consensus CDS Project	CCDS21009.1
International Mouse Knockout Project Status	Cyp2a12

Sequences

Length	Strain/Species
genomic	ENSMUSG00000060407	Ensembl Gene Model | MGI Sequence Detail	7718	C57BL/6J
transcript	ENSMUST00000075552	Ensembl | MGI Sequence Detail	1656	Not Applicable
polypeptide	ENSMUSP00000074990	Ensembl | MGI Sequence Detail	492	Not Applicable

All sequences(12) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(76 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008067	Cytochrome P450, E-class, group I, CYP2A-like
Protein Ontology	PR:000006219	cytochrome P450 2A12

References

(Earliest) J:23304 Iwasaki M, et al., Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction. Biochem J. 1993 Apr 15;291(Pt 2):569-73
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(22)

Other accession IDs

MGD-MRK-32094