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P2ry1
Gene Detail
Symbol

Name
ID
P2ry1
purinergic receptor P2Y, G-protein coupled 1
MGI:105049
Synonyms
P2Y1, P2Y1 receptor
Feature Type
protein coding gene
Genetic Map
Chromosome 3
29.24 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:61002795-61008982 bp, + strand
From VEGA annotation of GRCm38

  6188 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1926  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: P2Y purinoceptors 1/2/3/4/6
Gene Tree: P2ry1

Human
homologs
Human Homolog   P2RY1, purinergic receptor P2Y, G-protein coupled, 1
NCBI Gene ID 5028
neXtProt AC  NX_P47900
Human Synonyms  P2Y1
Human Chr (Location)  3q25.2; chr3:152834947-152838056 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for either one of two independently generated knock-out alleles exhibit decreased platelet aggregation, increased bleeding time, and resistance to induced thromboembolism.
 
Interactions
P2ry1 interacts with 297 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Expression
Literature Summary: (2 records)
Data Summary: Results (92)    Tissues (45)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 92
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000051935 (Evidence)
Ensembl Gene ModelENSMUSG00000027765 (Evidence)
Entrez Gene18441 (Evidence)
DFCITC1588821, TC1587363, TC1590503
DoTSDT.87039631, DT.55260467, DT.101174076
NIA Mouse Gene IndexU003280
Consensus CDS ProjectCCDS17377.1
International Mouse Knockout Project StatusP2ry1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051935 VEGA Gene Model | MGI Sequence Detail 6188 C57BL/6J ±  kb
transcript OTTMUST00000130723 VEGA | MGI Sequence Detail 3886 Not Applicable 
polypeptide OTTMUSP00000070027 VEGA | MGI Sequence Detail 373 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR000142 P2Y purinoceptor
Protein Ontology PR:000001568 P2Y purinoceptor 1
References
(Earliest) J:25964 Tokuyama Y, et al., Cloning of rat and mouse P2Y purinoceptors. Biochem Biophys Res Commun. 1995 Jun 6;211(1):211-8
(Latest) J:207408 Kalwa H, et al., Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3383-8
All references(69)
Other
accession IDs
MGD-MRK-32088

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory