About   Help   FAQ
Ttf1
Gene Detail
 Symbol
Name
ID
Ttf1
transcription termination factor, RNA polymerase I
MGI:105044
Feature Type protein coding gene
Genetic Map
Chromosome 2
19.38 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:29060262-29087656 bp, + strand
From VEGA annotation of GRCm38

  27395 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:137223  Vertebrate Homology Class
1 mouse; 1 rat

Gene Tree: Ttf1

Mutations,
alleles, and
phenotypes
All mutations/alleles(80) : Gene trapped(77) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ttf1 interacts with 213 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process chromatin remodeling, DNA-templated transcription, termination, ...
Component nucleus
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (54)    Tissues (54)    Images (4)
Theiler Stages: 2, 3, 4, 5, 11, 13, 17, 21, 23, 28
Assay TypeResults
RNA in situ 46
RT-PCR 8
cDNA source data(55)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(56) cDNA(55) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000011823 (Evidence)
Ensembl Gene ModelENSMUSG00000026803 (Evidence)
Entrez Gene22130 (Evidence)
UniGene252195
DFCITC1581543, TC1614172, TC1662573
DoTSDT.101707715, DT.110722954, DT.91336709, DT.94325739
NIA Mouse Gene IndexU001553
Consensus CDS ProjectCCDS38089.1
International Mouse Knockout Project StatusTtf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011823 VEGA Gene Model | MGI Sequence Detail 27395 C57BL/6J ±  kb
transcript OTTMUST00000027759 VEGA | MGI Sequence Detail 4160 Not Applicable 
polypeptide OTTMUSP00000012613 VEGA | MGI Sequence Detail 859 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(9) UniProt(3)
Polymorphisms SNPs within 2kb(237 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009057 Homeodomain-like
InterPro IPR017877 Myb-like domain
InterPro IPR001005 SANT/Myb domain
Protein Ontology PR:000016785 transcription termination factor 1
References (Earliest) J:24340 Evers R, et al., Different domains of the murine RNA polymerase I-specific termination factor mTTF-I serve distinct functions in transcription termination. EMBO J. 1995 Mar 15;14(6):1248-56
(Latest) J:196001 Yu H, et al., Deletion of STK40 protein in mice causes respiratory failure and death at birth. J Biol Chem. 2013 Feb 22;288(8):5342-52
All references(43)
Other
accession IDs
MGD-MRK-32083, MGI:2139261

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory