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Crybb1 Gene Detail
Summary
  • Symbol
    Crybb1
  • Name
    crystallin, beta B1
  • Synonyms
    3110006K12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:104992
    NCBI Gene: 12960
  • Gene Overview
    MyGene.info: CRYBB1
Location & Maps
more
  • Sequence Map
    Chr5:112255815-112269585 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13771 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 54.63 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    CRYBB1, crystallin beta B1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CRYBB1, crystallin beta B1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CATCN3, CTRCT17
  • Links
    NCBI Gene ID: 1414
    neXtProt AC: NX_P53674

  • Chr Location
    22q12.1; chr22:26599278-26618087 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CRYBB1 associations

Human Disease Mouse Models
       Cataract 17, Multiple Types; CTRCT17   OMIM: 611544
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Gene trapped
    11
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Crybb1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024817 VEGA Gene Model | MGI Sequence Detail 13771 C57BL/6J ±  kb
transcript OTTMUST00000061118 VEGA | MGI Sequence Detail 882 Not Applicable  
polypeptide OTTMUSP00000029911 VEGA | MGI Sequence Detail 250 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    28 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 309
    Genomic 3
    cDNA 305
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-31065, MGI:1920360
References
more
  • Summaries
    All 41
    Developmental Gene Expression 13
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:29365 Hulsebos TJ, et al., Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5. Genomics. 1995 Oct 10;29(3):712-8
  • Latest
    J:214344 Kerr CL, et al., AP-2alpha is required after lens vesicle formation to maintain lens integrity. Dev Dyn. 2014 Oct;243(10):1298-309

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory