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Crybb1
Gene Detail
 Symbol
Name
ID
Crybb1
crystallin, beta B1
MGI:104992
Synonyms 3110006K12Rik
Feature Type protein coding gene
Genetic Map
Chromosome 5
54.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:112255815-112269585 bp, + strand
From VEGA annotation of GRCm38

  13771 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1423  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: beta/gamma crystallins
Gene Tree: Crybb1

Human
homologs
Human Homolog CRYBB1, crystallin, beta B1
NCBI Gene ID 1414
neXtProt AC  NX_P53674
Human Synonyms  CATCN3, CTRCT17
Human Chr (Location)  22q12.1; chr22:26599398-26618027 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CRYBB1
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(11)
Interactions
Crybb1 interacts with 3 markers (Mir1895, Mir1963, Mir3092)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Function protein binding, structural constituent of eye lens
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (24)    Tissues (7)    Images (5)
Theiler Stages: 19, 24, 25, 28
Assay TypeResults
RNA in situ 3
Northern blot 3
RT-PCR 18
cDNA source data(305)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(309) Genomic(3) cDNA(305) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024817 (Evidence)
Ensembl Gene ModelENSMUSG00000029343 (Evidence)
Entrez Gene12960 (Evidence)
UniGene29488
DFCITC1572552
DoTSDT.101173221, DT.101738908
Consensus CDS ProjectCCDS19537.1
International Mouse Knockout Project StatusCrybb1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024817 VEGA Gene Model | MGI Sequence Detail 13771 C57BL/6J ±  kb
transcript OTTMUST00000061118 VEGA | MGI Sequence Detail 882 Not Applicable 
polypeptide OTTMUSP00000029911 VEGA | MGI Sequence Detail 250 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(14) UniProt(3)
Polymorphisms RFLP(2) : SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001064 Beta/gamma crystallin
InterPro IPR011024 Gamma-crystallin-related
Protein Ontology PR:000005911 beta-crystallin B1
References (Earliest) J:29365 Hulsebos TJ, et al., Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5. Genomics. 1995 Oct 10;29(3):712-8
(Latest) J:197830 Zhang R, et al., Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse. J Biol Chem. 2013 Apr 12;288(15):10275-85
All references(42)
Other
accession IDs
MGD-MRK-31065, MGI:1920360

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory