Crybb1
Gene Detail

Symbol Name ID

Crybb1 crystallin, beta B1 MGI:104992

Synonyms

3110006K12Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 5

54.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr5:112255815-112269585 bp, + strand From VEGA annotation of GRCm38   13771 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1423  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: beta/gamma crystallins
Gene Tree: Crybb1

Human homologs

Human Homolog		CRYBB1, crystallin, beta B1
NCBI Gene ID		1414
neXtProt AC		NX_P53674
Human Synonyms		CATCN3
Human Chr (Location)		22q12.1; chr22:26995362-27013991 (-)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human CRYBB1

Alleles and phenotypes

All alleles(11) : Gene trapped(11)

Gene Ontology (GO) classifications

All GO classifications: (1 annotations)

Function

structural constituent of eye lens

External Resources: FuncBase

Expression

Literature Summary: (11 records)
Data Summary: Results (24)    Tissues (7)    Images (5)
Theiler Stages: 19, 24, 25, 28

Assay Type	Results
RNA in situ	3
Northern blot	3
RT-PCR	18

cDNA source data(305)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(309) Genomic(3) cDNA(305) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000024817 (Evidence)
Ensembl Gene Model	ENSMUSG00000029343 (Evidence)
Entrez Gene	12960 (Evidence)
UniGene	29488
DFCI	TC1572552
DoTS	DT.101173221, DT.101738908
Consensus CDS Project	CCDS19537.1
International Mouse Knockout Project Status	Crybb1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024817	VEGA Gene Model | MGI Sequence Detail	13771	C57BL/6J
transcript	OTTMUST00000061118	VEGA | MGI Sequence Detail	882	Not Applicable
polypeptide	OTTMUSP00000029911	VEGA | MGI Sequence Detail	250	Not Applicable

All sequences(30) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(2) : SNPs(9 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001064	Beta/gamma crystallin
InterPro	IPR011024	Gamma-crystallin-related
Protein Ontology	PR:000005911	beta-crystallin B1

References

(Earliest) J:29365 Hulsebos TJ, et al., Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5. Genomics. 1995 Oct 10;29(3):712-8
(Latest) J:178731 Xie Q, et al., The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71
All references(40)

Other accession IDs

MGD-MRK-31065, MGI:1920360