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Ang2 Gene Detail
Summary
  • Symbol
    Ang2
  • Name
    angiogenin, ribonuclease A family, member 2
  • Synonyms
    Angrp, Rnase5b
  • Feature Type
    protein coding gene
  • IDs
    MGI:104984
    NCBI Gene: 11731
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:51195486-51195923 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.42 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104984
protein coding gene Chr14:51195324-51199148 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021277
protein coding gene Chr14:45172729-45173166 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0021671
protein coding gene Chr14:47037945-47038382 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0020540
protein coding gene Chr14:42441148-42444740 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0021179
protein coding gene Chr14:45627718-45628155 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0021700
protein coding gene Chr14:44944051-44944488 (-)
PWK/PhJ MGP_PWKPhJ_G0020289
protein coding gene Chr14:40740434-40740871 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021593
protein coding gene Chr16:32220111-32220548 (-)
WSB/EiJ MGP_WSBEiJ_G0020592
protein coding gene Chr14:45167987-45168424 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11731 NCBI Gene Model | MGI Sequence Detail 438 C57BL/6J ±  kb
transcript NM_007449 RefSeq | MGI Sequence Detail 438 Not Specified  
polypeptide Q64438 UniProt | EBI | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    Genomic 1
    cDNA 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-31057
References
more
  • Summaries
    All 42
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:28832 Brown WE, et al., The mouse angiogenin gene family: structures of an angiogenin-related protein gene and two pseudogenes. Genomics. 1995 Sep 1;29(1):200-6
  • Latest
    J:302415 Chatterjee A, et al., Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency. Int J Mol Sci. 2020 May 25;21(10)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory