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Tead2
Gene Detail
 Symbol
Name
ID
Tead2
TEA domain family member 2
MGI:104904
Synonyms Etdf, TEAD-2, TEF-4
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.19 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr7:45215753-45233635 bp, + strand
From VEGA annotation of GRCm38

  17883 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: transcriptional enhancer factor
Gene Tree: Tead2

Human
homologs
Human Homolog TEAD2, TEA domain family member 2
NCBI Gene ID 8463
neXtProt AC  NX_Q15562
Human Synonyms  ETF, TEAD-2, TEF4, TEF-4
Human Chr (Location)  19q13.3; chr19:49340595-49362457 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(32) : Gene trapped(27) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a functionally null allele of this gene exhibit no gross abnormalities and are fertile.
 
Phenotype Images(2)
Interactions
Tead2 interacts with 89 markers (Mir24-1, Mir24-2, Mir34b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process embryonic heart tube morphogenesis, hippo signaling, ...
Component intracellular, nucleus, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (26 records)
Data Summary: Results (576)    Tissues (131)    Images (45)
Theiler Stages: 1, 2, 3, 4, 5, 10, 11, 13, 14, 15, 16, 17, 19, 21, 23, 27, 28
Assay TypeResults
RNA in situ 544
Northern blot 10
RT-PCR 22
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) Genomic(3) cDNA(21) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025380 (Evidence)
Ensembl Gene ModelENSMUSG00000030796 (Evidence)
Entrez Gene21677 (Evidence)
DFCITC1572516, TC1753645
DoTSDT.101368769, DT.101403891, DT.102557626, DT.535745, DT.99862906
NIA Mouse Gene IndexU008068
Consensus CDS ProjectCCDS21236.1, CCDS71957.1
International Mouse Knockout Project StatusTead2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025380 VEGA Gene Model | MGI Sequence Detail 17883 C57BL/6J ±  kb
transcript OTTMUST00000062479 VEGA | MGI Sequence Detail 3396 Not Applicable 
polypeptide OTTMUSP00000030805 VEGA | MGI Sequence Detail 445 Not Applicable 

For the selected sequences
All sequences(77) RefSeq(11) UniProt(7)
Polymorphisms RFLP(1) : SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000818 TEA/ATTS
InterPro IPR016361 Transcriptional enhancer factor
Protein Ontology PR:000016219 transcriptional enhancer factor TEF-4
References (Earliest) J:48110 Burglin TR, The TEA domain: a novel, highly conserved DNA-binding motif [letter]. Cell. 1991 Jul 12;66(1):11-2
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(66)
Other
accession IDs
MGD-MRK-29058

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory