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Tead2
Gene Detail
Symbol

Name
ID
Tead2
TEA domain family member 2
MGI:104904
Synonyms
Etdf, TEAD-2, TEF-4
Feature Type
protein coding gene
Genetic Map
Chromosome 7
29.19 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr7:45215753-45233635 bp, + strand
From VEGA annotation of GRCm38

  17883 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: TEAD2
Protein SuperFamily: transcriptional enhancer factor
Gene Tree: Tead2

Human
homologs
TEAD2, TEA domain family member 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8463
neXtProt AC: NX_Q15562

Human Synonyms: ETF, TEAD-2, TEF4, TEF-4

Human Chr (Location): 19q13.3; chr19:49340595-49362457 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(32) : Gene trapped(27) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a functionally null allele of this gene exhibit no gross abnormalities and are fertile.
 
Phenotype Images(2)
Interactions
Tead2 interacts with 89 markers (Mir24-1, Mir24-2, Mir34b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process cellular response to retinoic acid, embryonic heart tube morphogenesis, ...
Component intracellular, nucleus, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (26 records)
Data Summary: Results (587)    Tissues (141)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 555
Northern blot 10
RT-PCR 22
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(29) Genomic(3) cDNA(22) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000025380 (Evidence)
Ensembl Gene Model ENSMUSG00000030796 (Evidence)
Entrez Gene 21677 (Evidence)
DFCI TC1753645, TC1572516
DoTS DT.102557626, DT.535745, DT.101403891, DT.101368769, DT.99862906
NIA Mouse Gene Index U008068
Consensus CDS Project CCDS21236.1, CCDS71957.1
International Mouse Phenotyping Consortium Status Tead2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025380 VEGA Gene Model | MGI Sequence Detail 17883 C57BL/6J ±  kb
transcript OTTMUST00000062478 VEGA | MGI Sequence Detail 2115 Not Applicable 
polypeptide OTTMUSP00000030804 VEGA | MGI Sequence Detail 445 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(10) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000818 TEA/ATTS
InterPro IPR016361 Transcriptional enhancer factor
Protein Ontology PR:000016219 transcriptional enhancer factor TEF-4
References
(Earliest) J:48110 Burglin TR, The TEA domain: a novel, highly conserved DNA-binding motif [letter]. Cell. 1991 Jul 12;66(1):11-2
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(64)
Other
accession IDs
MGD-MRK-29058

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory