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Nup88 Gene Detail
Summary
  • Symbol
    Nup88
  • Name
    nucleoporin 88
  • Synonyms
    Nup84, Prei2
  • Feature Type
    protein coding gene
  • IDs
    MGI:104900
    NCBI Gene: 19069
  • Gene Overview
    MyGene.info: NUP88
Location & Maps
more
  • Sequence Map
    Chr11:70943058-70969973 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26916 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 43.21 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NUP88, nucleoporin 88
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP88, nucleoporin 88
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 4927
    neXtProt AC: NX_Q99567

  • Chr Location
    17p13.2; chr17:5386026-5419739 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 1901
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: NUP88
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    32
  • Chemically induced (other)
    1
  • Gene trapped
    28
  • Targeted
    3
  • Genomic Mutations
    2 involving Nup88
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006081 VEGA Gene Model | MGI Sequence Detail 26916 C57BL/6J ±  kb
transcript OTTMUST00000013737 VEGA | MGI Sequence Detail 2450 Not Applicable  
polypeptide OTTMUSP00000006374 VEGA | MGI Sequence Detail 753 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    170 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000011524 nuclear pore complex protein Nup88
  • InterPro Domains
    IPR019321 Nucleoporin Nup88
Molecular
Reagents
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  • All nucleic 187
    Genomic 2
    cDNA 183
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-29053
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:16710 Temeles GL, et al., Expression patterns of novel genes during mouse preimplantation embryogenesis. Mol Reprod Dev. 1994 Feb;37(2):121-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory