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Mob4 Gene Detail
Summary
  • Symbol
    Mob4
  • Name
    MOB family member 4, phocein
  • Synonyms
    2610109B12Rik, Mobkl3, Prei3
  • Feature Type
    protein coding gene
  • IDs
    MGI:104899
    NCBI Gene: 19070
  • Gene Overview
    MyGene.info: MOB4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:55131245-55154899 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 28.03 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104899
protein coding gene Chr1:55131231-55154899 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016032
protein coding gene Chr1:54853839-54880809 (+)
A/J MGP_AJ_G0016015
protein coding gene Chr1:52944427-52968359 (+)
AKR/J MGP_AKRJ_G0015971
protein coding gene Chr1:54381488-54404629 (+)
BALB/cJ MGP_BALBcJ_G0015970
protein coding gene Chr1:52993068-53017397 (+)
C3H/HeJ MGP_C3HHeJ_G0015802
protein coding gene Chr1:54621288-54648589 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016423
protein coding gene Chr1:57120166-57148086 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014145
protein coding gene Chr1:49022614-49057170 (+)
CAST/EiJ MGP_CASTEiJ_G0015384
protein coding gene Chr1:53903206-53926732 (+)
CBA/J MGP_CBAJ_G0015774
protein coding gene Chr1:58745738-58774667 (+)
DBA/2J MGP_DBA2J_G0015875
protein coding gene Chr1:52365457-52389362 (+)
FVB/NJ MGP_FVBNJ_G0015877
protein coding gene Chr1:51712319-51737143 (+)
LP/J MGP_LPJ_G0015947
protein coding gene Chr1:55678441-55705923 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015897
protein coding gene Chr1:61843678-61867497 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016470
protein coding gene Chr1:54324109-54352053 (+)
PWK/PhJ MGP_PWKPhJ_G0015170
protein coding gene Chr1:51728349-51752844 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014951
protein coding gene Chr1:53958908-53984697 (+)
WSB/EiJ MGP_WSBEiJ_G0015447
protein coding gene Chr1:54015147-54041326 (+)



Homology
more
  • Human Ortholog
    MOB4, MOB family member 4, phocein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MOB4, MOB family member 4, phocein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2C4D, CGI-95, MOB1, MOB3, MOBKL3, PHOCN, PREI3
  • Links
    NCBI Gene ID: 25843
    neXtProt AC: NX_Q9Y3A3
    UniProt: Q9Y3A3

  • Chr Location
    2q33.1; chr2:197515571-197553699 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9116
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MOB4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    76
  • Chemically induced (other)
    1
  • Gene trapped
    72
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Mob4
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19070 NCBI Gene Model | MGI Sequence Detail 23655 C57BL/6J ±  kb
transcript NM_025283 RefSeq | MGI Sequence Detail 2845 C57BL/6  
polypeptide Q6PEB6 UniProt | EBI | MGI Sequence Detail 225 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 14
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-29052, MGI:1917702
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory