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Gpcpd1 Gene Detail
Summary
  • Symbol
    Gpcpd1
  • Name
    glycerophosphocholine phosphodiesterase 1
  • Synonyms
    2310004G06Rik, 2310032D16Rik, mKIAA1434, Prei4
  • Feature Type
    protein coding gene
  • IDs
    MGI:104898
    NCBI Gene: 74182
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:132529082-132578258 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 64.57 cM, cytoband F3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104898
protein coding gene Chr2:132529082-132587729 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026543
protein coding gene Chr2:136123518-136189605 (-)
A/J MGP_AJ_G0026507
protein coding gene Chr2:130578696-130637689 (-)
AKR/J MGP_AKRJ_G0026481
protein coding gene Chr2:134349071-134411619 (-)
BALB/cJ MGP_BALBcJ_G0026519
protein coding gene Chr2:130977023-131037302 (-)
C3H/HeJ MGP_C3HHeJ_G0026262
protein coding gene Chr2:134786453-134844988 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026964
protein coding gene Chr2:140251282-140317725 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024341
protein coding gene Chr2:125310943-125365161 (-)
CAST/EiJ MGP_CASTEiJ_G0025723
protein coding gene Chr2:135127350-135187091 (-)
CBA/J MGP_CBAJ_G0026242
protein coding gene Chr2:145531366-145599898 (-)
DBA/2J MGP_DBA2J_G0026376
protein coding gene Chr2:129970134-130028941 (-)
FVB/NJ MGP_FVBNJ_G0026340
protein coding gene Chr2:128597716-128657220 (-)
LP/J MGP_LPJ_G0026480
protein coding gene Chr2:136343811-136408555 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026360
protein coding gene Chr2:149278100-149339556 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027019
protein coding gene Chr2:134311482-134370389 (-)
PWK/PhJ MGP_PWKPhJ_G0025459
protein coding gene Chr2:129569509-129629125 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025261
protein coding gene Chr2:133466451-133525449 (-)
WSB/EiJ MGP_WSBEiJ_G0025797
protein coding gene Chr2:135227377-135295531 (-)



Homology
more
  • Human Ortholog
    GPCPD1, glycerophosphocholine phosphodiesterase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GPCPD1, glycerophosphocholine phosphodiesterase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EDI3, GDE5, GDPD6, PREI4
  • Links
    NCBI Gene ID: 56261
    neXtProt AC: NX_Q9NPB8
    UniProt: Q9NPB8

  • Chr Location
    20p12.3; chr20:5544434-5611026 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10478
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GPCPD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    8
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Gpcpd1
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 74182 NCBI Gene Model | MGI Sequence Detail 49177 C57BL/6J ±  kb
transcript NM_001355649 RefSeq | MGI Sequence Detail 3725 C57BL/6  
polypeptide Q8C0L9 UniProt | EBI | MGI Sequence Detail 675 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000031695 glycerophosphocholine phosphodiesterase GPCPD1
  • EC
  • InterPro Domains
    IPR013784 Carbohydrate-binding-like fold
    IPR002044 Carbohydrate binding module family 20
    IPR034839 Glycerophosphocholine phosphodiesterase GPCPD1, CBM20 domain
    IPR030395 Glycerophosphodiester phosphodiesterase domain
    IPR033506 Glycerophosphodiester phosphodiesterase Gde1
    IPR013783 Immunoglobulin-like fold
    IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Molecular
Reagents
less
  • All nucleic 27
    cDNA 24
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-29051, MGI:1916759, MGI:1921432
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:219311 Corda D, et al., The emerging physiological roles of the glycerophosphodiesterase family. FEBS J. 2014 Feb;281(4):998-1016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory