Targeted mutation of this gene results in embryonic lethality preceded by growth retardation and abnormal cellular organization in several tissues, including the hindbrain and somites. Mice with conditional deletions exhibit increased apoptosis in affected cells.
|VEGA Gene Model||OTTMUSG00000021414 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000029249 (Evidence)|
|Entrez Gene||19712 (Evidence)|
|DFCI||TC1613389, TC1629649, TC1647156, TC1680681, TC1688514|
|DoTS||DT.101142681, DT.101375132, DT.492464, DT.91569213, DT.94020992, DT.94223288, DT.97411880|
|NIA Mouse Gene Index||U042648|
|Consensus CDS Project||CCDS19372.1|
|International Mouse Phenotyping Consortium Status||Rest|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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