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Ubp1 Gene Detail
Summary
  • Symbol
    Ubp1
  • Name
    upstream binding protein 1
  • Synonyms
    LBP-1a, LBP-1b, NF2d9
  • Feature Type
    protein coding gene
  • IDs
    MGI:104889
    NCBI Gene: 22221
  • Gene Overview
    MyGene.info: UBP1
  • Alliance
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:113930934-113977202 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 64.14 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104889
protein coding gene Chr9:113930934-113977202 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035381
protein coding gene Chr9:116318128-116369241 (+)
A/J MGP_AJ_G0035362
protein coding gene Chr9:111987677-112037522 (+)
AKR/J MGP_AKRJ_G0035293
protein coding gene Chr9:114841147-114890806 (+)
BALB/cJ MGP_BALBcJ_G0035357
protein coding gene Chr9:111812621-111860001 (+)
C3H/HeJ MGP_C3HHeJ_G0035065
protein coding gene Chr9:115360566-115410699 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035878
protein coding gene Chr9:119476566-119524007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032765
protein coding gene Chr9:109139746-109186570 (+)
CAST/EiJ MGP_CASTEiJ_G0034371
protein coding gene Chr9:115217511-115265707 (+)
CBA/J MGP_CBAJ_G0035032
protein coding gene Chr9:123874972-123929805 (+)
DBA/2J MGP_DBA2J_G0035190
protein coding gene Chr9:111457271-111506410 (+)
FVB/NJ MGP_FVBNJ_G0035137
protein coding gene Chr9:110277582-110324594 (+)
LP/J MGP_LPJ_G0035270
protein coding gene Chr9:116611876-116662870 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035178
protein coding gene Chr9:125121531-125175712 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035899
protein coding gene Chr9:115244973-115293053 (+)
PWK/PhJ MGP_PWKPhJ_G0034076
protein coding gene Chr9:111750590-111799359 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033911
protein coding gene Chr9:115300280-115346714 (+)
WSB/EiJ MGP_WSBEiJ_G0034491
protein coding gene Chr9:115085710-115138419 (+)



Homology
more
  • Human Ortholog
    UBP1, upstream binding protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    UBP1, upstream binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LBP-1a, LBP1A, LBP1B, LBP-1B
  • Links
    NCBI Gene ID: 7342
    neXtProt AC: NX_Q9NZI7
    UniProt: Q9NZI7

  • Chr Location
    3p22.3; chr3:33388336-33440405 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene die during gestation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22221 NCBI Gene Model | MGI Sequence Detail 46269 C57BL/6J ±  kb
    transcript NM_001083319 RefSeq | MGI Sequence Detail 3857 C57BL/6  
    polypeptide Q811S7 UniProt | EBI | MGI Sequence Detail 540 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 21
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-29042
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 9
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:27225 Sueyoshi T, et al., A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver. Mol Cell Biol. 1995 Aug;15(8):4158-66
    • Latest
      J:253164 Lin JC, et al., RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes. Sci Rep. 2016 Feb 9;6:20665

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory