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Psma2 Gene Detail
Summary
  • Symbol
    Psma2
  • Name
    proteasome (prosome, macropain) subunit, alpha type 2
  • Synonyms
    Lmpc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:104885
    NCBI Gene: 19166
  • Gene Overview
    MyGene.info: PSMA2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:14613242-14625673 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 5.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104885
protein coding gene Chr13:14613240-14674236 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020245
protein coding gene Chr13:11599817-11612739 (+)
A/J MGP_AJ_G0020203
protein coding gene Chr13:11507723-11523188 (+)
AKR/J MGP_AKRJ_G0020177
protein coding gene Chr13:11656478-11669954 (+)
BALB/cJ MGP_BALBcJ_G0020189
protein coding gene Chr13:11480202-11493181 (+)
C3H/HeJ MGP_C3HHeJ_G0019993
protein coding gene Chr13:11794050-11805932 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020633
protein coding gene Chr13:12225090-12241675 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018239
protein coding gene Chr13:10204251-10215223 (+)
CAST/EiJ MGP_CASTEiJ_G0019526
protein coding gene Chr13:11462852-11476008 (+)
CBA/J MGP_CBAJ_G0019957
protein coding gene Chr13:12581177-12598673 (+)
DBA/2J MGP_DBA2J_G0020076
protein coding gene Chr13:11158260-11170112 (+)
FVB/NJ MGP_FVBNJ_G0020057
protein coding gene Chr13:10920731-10932446 (+)
LP/J MGP_LPJ_G0020146
protein coding gene Chr13:11813477-11825264 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020094
protein coding gene Chr13:12744303-12767722 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020660
protein coding gene Chr13:11456403-11476818 (+)
PWK/PhJ MGP_PWKPhJ_G0019290
protein coding gene Chr13:11237785-11250310 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019097
protein coding gene Chr13:10613257-10624398 (+)
WSB/EiJ MGP_WSBEiJ_G0019588
protein coding gene Chr13:11469373-11482113 (+)



Homology
more
  • Human Ortholog
    PSMA2, proteasome subunit alpha 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    PSMA2, proteasome subunit alpha 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HC3, MU, PMSA2, PSC2
  • Links
    NCBI Gene ID: 5683
    neXtProt AC: NX_P25787
    UniProt: P25787

  • Chr Location
    7p14.1; chr7:42916861-42932206 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2081
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PSMA2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19166 NCBI Gene Model | MGI Sequence Detail 12432 C57BL/6J ±  kb
transcript NM_008944 RefSeq | MGI Sequence Detail 963 C57BL/6  
polypeptide P49722 UniProt | EBI | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 216
    cDNA 216

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11825, MGD-MRK-29038
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:4568 Woodward EC, et al., Chromosomal mapping of the non-MHC linked proteasome genes. J Immunol. 1993;150(8):43A (Abstr.)
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory