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Psma2 Gene Detail
Summary
  • Symbol
    Psma2
  • Name
    proteasome subunit alpha 2
  • Synonyms
    Lmpc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:104885
    NCBI Gene: 19166
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:14787827-14800258 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 5.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    465 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104885
 protein coding gene Chr13:14787825-14848821 (+)
129S1/SvImJ ENSMUSG00200013296
 protein coding gene Chr13:12001227-12062223 (+)
A/J ENSMUSG00195036773
 protein coding gene Chr13:11083782-11144794 (+)
AKR/J ENSMUSG00220026296
 protein coding gene Chr13:11094116-11161531 (+)
BALB/cJ ENSMUSG00180034545
 protein coding gene Chr13:11432811-11493814 (+)
C3H/HeJ ENSMUSG00175033251
 protein coding gene Chr13:11534117-11595125 (+)
C57BL/6NJ ENSMUSG00215016696
 protein coding gene Chr13:11541185-11602192 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018239
 protein coding gene Chr13:10204251-10215223 (+)
CAST/EiJ ENSTCUG00005013620
 protein coding gene Chr13:11678130-11738123 (+)
CBA/J ENSMUSG00210028745
 protein coding gene Chr13:11399692-11460688 (+)
DBA/2J ENSMUSG00185012994
 protein coding gene Chr13:12094460-12155453 (+)
FVB/NJ ENSMUSG00205042616
 protein coding gene Chr13:11331609-11392708 (+)
JF1/MsJ ENSUMUG00000012507
 protein coding gene Chr13:11920762-11988260 (+)
LP/J ENSMUSG00230032461
 protein coding gene Chr13:21503443-21564434 (+)
NOD/ShiLtJ ENSMUSG00190022080
 protein coding gene Chr13:11408148-11469250 (+)
NZO/HlLtJ ENSMUSG00225032160
 protein coding gene Chr13:15269669-15330688 (+)
PWK/PhJ ENSLUMG00010025729
 protein coding gene Chr13:10871838-10939145 (+)
SPRET/EiJ ENSMSPG00010018405
 protein coding gene Chr13:10534420-10545503 (+)
WSB/EiJ ENSIUOG00005034342
 protein coding gene Chr13:10751502-10818716 (+)



Homology
more
  • Human Ortholog
    PSMA2, proteasome 20S subunit alpha 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMA2, proteasome 20S subunit alpha 2
  • Synonyms
    HC3, MU, PMSA2, PSC2
  • Links
    NCBI Gene ID: 5683
    UniProt: P25787

  • Chr Location
    7p14.1; chr7:42916828-42932223 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    214
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19166 NCBI Gene Model | MGI Sequence Detail 12432 C57BL/6J ±  kb
transcript NM_008944 RefSeq | MGI Sequence Detail 963 C57BL/6  
polypeptide P49722 UniProt | EBI | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 216
    cDNA 216

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11825, MGD-MRK-29038
References
more
  • Summaries
    All 47
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 10
  • Earliest
    J:4568 Woodward EC, et al., Chromosomal mapping of the non-MHC linked proteasome genes. J Immunol. 1993;150(8):43A (Abstr.)
  • Latest
    J:338299 Xing L, et al., Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice. Cell Rep. 2023 Jun 28;42(7):112706
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory