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Psmb6 Gene Detail
Summary
  • Symbol
    Psmb6
  • Name
    proteasome (prosome, macropain) subunit, beta type 6
  • Synonyms
    Lmp19, Mpnd, subunit 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:104880
    NCBI Gene: 19175
  • Gene Overview
    MyGene.info: PSMB6
Location & Maps
more
  • Sequence Map
    Chr11:70525367-70527858 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      2492 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.99 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PSMB6, proteasome subunit beta 6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PSMB6, proteasome subunit beta 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DELTA, LMPY, Y
  • Links
    NCBI Gene ID: 5694
    neXtProt AC: NX_P28072

  • Chr Location
    17p13; chr17:4796144-4798503 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    3
  • Genomic Mutations
    2 involving Psmb6
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    5
  • Tissues
    5
  • cDNA Data
    228
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006054 VEGA Gene Model | MGI Sequence Detail 2492 C57BL/6J ±  kb
transcript OTTMUST00000013639 VEGA | MGI Sequence Detail 798 Not Applicable  
polypeptide OTTMUSP00000006323 VEGA | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    80 from dbSNP Build 142
  • RFLP
    2
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 231
    Genomic 3
    cDNA 228

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18666, MGD-MRK-24102, MGD-MRK-29033
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:19482 Fruh K, et al., Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex. EMBO J. 1994 Jul 15;13(14):3236-44
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory