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Ppp1cc
Gene Detail
 Symbol
Name
ID
Ppp1cc
protein phosphatase 1, catalytic subunit, gamma isoform
MGI:104872
Synonyms PP1, PP1C gamma, PP1C gamma 1, PP1C gamma 2
Feature Type protein coding gene
Genetic Map
Chromosome 5
62.20 cM, cytoband F-G1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:122158278-122175273 bp, + strand
From VEGA annotation of GRCm38

  16996 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135423  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: serine/threonine-protein phosphatase, conventional type
Gene Tree: Ppp1cc

Alleles
and
phenotypes
All alleles(46) : Gene trapped(41) Targeted(5)
 
Homozygotes for a targeted null mutation exhibit male infertility due to severely impaired spermiogenesis.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process neuron differentiation, protein dephosphorylation, ...
Component dendritic spine, mitochondrial outer membrane, ...
Function protein binding, protein N-terminus binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (30)    Tissues (30)    Images (9)
Theiler Stages: 19, 21, 23, 28
Assay TypeResults
RNA in situ 29
Western blot 1
cDNA source data(20)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(22) Genomic(2) cDNA(20)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016349 (Evidence)
Ensembl Gene ModelENSMUSG00000004455 (Evidence)
Entrez Gene19047 (Evidence)
Consensus CDS ProjectCCDS19643.1
International Mouse Knockout Project StatusPpp1cc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016349 VEGA Gene Model | MGI Sequence Detail 16996 C57BL/6J ±  kb
transcript OTTMUST00000039309 VEGA | MGI Sequence Detail 1442 Not Applicable 
polypeptide OTTMUSP00000017568 VEGA | MGI Sequence Detail 337 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(4)
Polymorphisms SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000013104 serine/threonine-protein phosphatase PP1-gamma catalytic subunit
References (Earliest) J:30044 Ohkura H, et al., The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. Cell. 1989 Jun 16;57(6):997-1007
(Latest) J:203985 Sinha N, et al., Selective ablation of Ppp1cc gene in testicular germ cells causes oligo-teratozoospermia and infertility in mice. Biol Reprod. 2013 Nov;89(5):128
All references(64)
Other
accession IDs
MGD-MRK-28171

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory