About   Help   FAQ
Ppp1cc
Gene Detail
Symbol

Name
ID
Ppp1cc
protein phosphatase 1, catalytic subunit, gamma isoform
MGI:104872
Synonyms
PP1, PP1C gamma, PP1C gamma 1, PP1C gamma 2
Feature Type
protein coding gene
Genetic Map
Chromosome 5
62.20 cM, cytoband F-G1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:122158278-122175273 bp, + strand
From VEGA annotation of GRCm38

  16996 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135423  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: serine/threonine-protein phosphatase, conventional type
Gene Tree: Ppp1cc

Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(41) Targeted(6)
 
Homozygotes for a targeted null mutation exhibit male infertility due to severely impaired spermiogenesis.
 
Interactions
Ppp1cc interacts with 212 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process neuron differentiation, protein dephosphorylation, ...
Component dendritic spine, mitochondrial outer membrane, ...
Function lamin binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (30)    Tissues (30)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 29
Western blot 1
cDNA source data(20)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase ppp1cc ; ZFIN ppp1cc    NEW 
Molecular
reagents
All nucleic(22) Genomic(2) cDNA(20)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000016349 (Evidence)
Ensembl Gene Model ENSMUSG00000004455 (Evidence)
Entrez Gene 19047 (Evidence)
Consensus CDS Project CCDS19643.1
International Mouse Phenotyping Consortium Status Ppp1cc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016349 VEGA Gene Model | MGI Sequence Detail 16996 C57BL/6J ±  kb
transcript OTTMUST00000039309 VEGA | MGI Sequence Detail 1442 Not Applicable 
polypeptide OTTMUSP00000017568 VEGA | MGI Sequence Detail 337 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(4)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000013104 serine/threonine-protein phosphatase PP1-gamma catalytic subunit
References
(Earliest) J:30044 Ohkura H, et al., The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. Cell. 1989 Jun 16;57(6):997-1007
(Latest) J:204598 MacLeod G, et al., PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis. Reproduction. 2014 Jan;147(1):1-12
All references(64)
Other
accession IDs
MGD-MRK-28171

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory