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Pdia4 Gene Detail
Summary
  • Symbol
    Pdia4
  • Name
    protein disulfide isomerase associated 4
  • Synonyms
    Cai, Erp72, ERp72, U48620
  • Feature Type
    protein coding gene
  • IDs
    MGI:104864
    NCBI Gene: 12304
  • Gene Overview
    MyGene.info: PDIA4
Location & Maps
more
  • Sequence Map
    Chr6:47796141-47813430 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      17290 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 22.94 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    PDIA4, protein disulfide isomerase family A member 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PDIA4, protein disulfide isomerase family A member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ERP70, ERp-72, ERP72
  • Links
    NCBI Gene ID: 9601
    neXtProt AC: NX_P13667

  • Chr Location
    7q35; chr7:149003051-149028690 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    11
  • Gene trapped
    7
  • Targeted
    4
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    27
  • Tissues
    5
  • cDNA Data
    155
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057218 VEGA Gene Model | MGI Sequence Detail 17290 C57BL/6J ±  kb
transcript OTTMUST00000140860 VEGA | MGI Sequence Detail 2399 Not Applicable  
polypeptide OTTMUSP00000073705 VEGA | MGI Sequence Detail 641 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    117 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 157
    Genomic 2
    cDNA 155

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-28161, MGI:1201401, MGI:1930896, MGI:2141523
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:22695 Gough NM, et al., An mRNA sharing sequences with a variant granulocyte-macrophage colony stimulating factor cDNA clone. Nucleic Acids Res. 1987 Dec 23;15(24):10584
  • Latest
    J:206668 Liegel RP, et al., Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. Am J Hum Genet. 2013 Dec 5;93(6):1001-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory