Daf2
Gene Detail

Symbol Name ID

Daf2 decay accelerating factor 2 MGI:104849

Synonyms

complement-transmembrane, Daf-TM, TM-DAF

Feature Type

protein coding gene

Genetic Map

Chromosome 1

56.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr1:130388537-130423009 bp, - strand From VEGA annotation of GRCm38   34473 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:88791  Vertebrate Homology Class
2 mouse; 1 chimpanzee

Protein SuperFamily: decay-accelerating factor DAF (CD55 antigen)
Gene Tree: Daf2

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	complement activation, classical pathway, innate immune response
Component	integral to membrane, membrane
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (133)    Tissues (19)    Images (24)
Theiler Stages: 23

Assay Type	Results
RNA in situ	133

cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(9) Genomic(1) cDNA(8)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000025172 (Evidence)
Ensembl Gene Model	ENSMUSG00000026401 (Evidence)
Entrez Gene	13137 (Evidence)
DFCI	TC1589376, TC1608539, TC1698045
DoTS	DT.55150991, DT.55258947, DT.87050910, DT.94208348
Consensus CDS Project	CCDS35699.1
International Mouse Knockout Project Status	Daf2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000025172	VEGA Gene Model | MGI Sequence Detail	34473	C57BL/6J
transcript	OTTMUST00000061937	VEGA | MGI Sequence Detail	1325	Not Applicable
polypeptide	OTTMUSP00000030474	VEGA | MGI Sequence Detail	400	Not Applicable

All sequences(35) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(132 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR016060	Complement control module
InterPro	IPR000436	Sushi/SCR/CCP
Protein Ontology	PR:000006176	complement decay-accelerating factor transmembrane isoform

References

(Earliest) J:29133 Spicer AP, et al., Molecular cloning and chromosomal localization of the mouse decay-accelerating factor genes. Duplicated genes encode glycosylphosphatidylinositol-anchored and transmembrane forms. J Immunol. 1995 Sep 15;155(6):3079-91
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Other accession IDs

MGD-MRK-28145, MGI:2138208