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Spata13 Gene Detail
Summary
  • Symbol
    Spata13
  • Name
    spermatogenesis associated 13
  • Synonyms
    ESTM11, mKIAA1112
  • Feature Type
    protein coding gene
  • IDs
    MGI:104838
    NCBI Gene: 219140
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:60634001-60764556 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 31.77 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2088 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104838
protein coding gene Chr14:60485192-60764556 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021433
protein coding gene Chr14:54963959-55110571 (+)
A/J MGP_AJ_G0021392
protein coding gene Chr14:53785616-53920250 (+)
AKR/J MGP_AKRJ_G0021367
protein coding gene Chr14:55698645-55839687 (+)
BALB/cJ MGP_BALBcJ_G0021397
protein coding gene Chr14:53741790-53877609 (+)
C3H/HeJ MGP_C3HHeJ_G0021175
protein coding gene Chr14:55357917-55499886 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021836
protein coding gene Chr14:57673579-57827225 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019376
protein coding gene Chr14:51808190-51939489 (+)
CAST/EiJ MGP_CASTEiJ_G0020691
protein coding gene Chr14:51746237-51888142 (+)
CBA/J MGP_CBAJ_G0021142
protein coding gene Chr14:59321594-59471905 (+)
DBA/2J MGP_DBA2J_G0021265
protein coding gene Chr14:53471661-53602565 (+)
FVB/NJ MGP_FVBNJ_G0021243
protein coding gene Chr14:52876700-53010495 (+)
LP/J MGP_LPJ_G0021339
protein coding gene Chr14:56021122-56161047 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021272
protein coding gene Chr14:58678949-58820214 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021859
protein coding gene Chr14:54852413-54991937 (+)
PWK/PhJ MGP_PWKPhJ_G0020435
protein coding gene Chr14:50120258-50257373 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020268
protein coding gene Chr14:50804166-50941651 (+)
WSB/EiJ MGP_WSBEiJ_G0020744
protein coding gene Chr14:55170349-55307486 (+)



Homology
more
  • Human Ortholog
    SPATA13, spermatogenesis associated 13
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SPATA13, spermatogenesis associated 13
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARHGEF29, ASEF2
  • Links
    NCBI Gene ID: 221178
    neXtProt AC: NX_Q96N96
    UniProt: Q96N96

  • Chr Location
    13q12.12; chr13:23979626-24307074 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    10 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and overtly normal but show a significant reduction in the number and size of intestinal adenomas in conjunction with ApcMin heterozygotes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021990 Ensembl Gene Model | MGI Sequence Detail 130556 C57BL/6J ±  kb
transcript ENSMUST00000022566 Ensembl | MGI Sequence Detail 7517 Not Applicable  
polypeptide ENSMUSP00000022566 Ensembl | MGI Sequence Detail 1244 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    9 Sequences
  • InterPro Domains
    IPR000219 Dbl homology (DH) domain
    IPR035899 Dbl homology (DH) domain superfamily
    IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
    IPR011993 PH-like domain superfamily
    IPR001849 Pleckstrin homology domain
    IPR001452 SH3 domain
    IPR036028 SH3-like domain superfamily
Molecular
Reagents
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  • All nucleic 109
    cDNA 109

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-28132, MGI:1353612
References
more
  • Summaries
    All 44
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:28401 Bettenhausen B, et al., Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. Genomics. 1995 Aug 10;28(3):436-41
  • Latest
    J:237193 Chaboub LS, et al., Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci. 2016 Nov 23;36(47):11904-11917

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory