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Plaa Gene Detail
Summary
  • Symbol
    Plaa
  • Name
    phospholipase A2, activating protein
  • Synonyms
    D4Ertd618e, Ufd3
  • Feature Type
    protein coding gene
  • IDs
    MGI:104810
    NCBI Gene: 18786
  • Gene Overview
    MyGene.info: PLAA
Location & Maps
more
  • Sequence Map
    Chr4:94567514-94603244 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35731 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PLAA, phospholipase A2 activating protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PLAA, phospholipase A2 activating protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DOA1, PLA2P, PLAP
  • Links
    NCBI Gene ID: 9373
    neXtProt AC: NX_Q9Y263

  • Chr Location
    9p21; chr9:26903370-26947470 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 3138
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PLAA
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    24
  • Chemically induced (other)
    2
  • Gene trapped
    18
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    3 involving Plaa
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007850 VEGA Gene Model | MGI Sequence Detail 35731 C57BL/6J ±  kb
transcript OTTMUST00000017870 VEGA | MGI Sequence Detail 2784 Not Applicable  
polypeptide OTTMUSP00000008214 VEGA | MGI Sequence Detail 794 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    148 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
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MGD-MRK-28104, MGI:1277105, MGI:2140330, MGI:2140438, MGI:2140559
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:28587 Clark MA, et al., Cloning of a phospholipase A2-activating protein. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5418-22
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory