Fkbp10
Gene Detail

Symbol Name ID

Fkbp10 FK506 binding protein 10 MGI:104769

Synonyms

65kDa, Fkbp1-rs, Fkbp6, FKBP65, Fkbp-rs1

Feature Type

protein coding gene

Genetic Map

Chromosome 11

63.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)

Sequence Map

Chr11:100415697-100424824 bp, + strand From VEGA annotation of GRCm38   9128 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7718  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fkbp10

Human homologs

Human Homolog		FKBP10, FK506 binding protein 10, 65 kDa
NCBI Gene ID		60681
neXtProt AC		NX_Q96AY3
Human Synonyms		FKBP65, hFKBP65, OI11, OI6, PPIASE
Human Chr (Location)		17q21.2; chr17:39968962-39979469 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human FKBP10

Alleles and phenotypes

All alleles(7) : Targeted(4) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	peptidyl-proline modification, protein folding
Component	endoplasmic reticulum, membrane
Function	calcium ion binding, FK506 binding, ...

External Resources: FuncBase

Expression

cDNA source data(102)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(102) cDNA(102)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000006274 (Evidence)
Ensembl Gene Model	ENSMUSG00000001555 (Evidence)
Entrez Gene	14230 (Evidence)
UniGene	3894
DFCI	TC1572591
DoTS	DT.91358033
NIA Mouse Gene Index	U013338
EC	5.2.1.8
Consensus CDS Project	CCDS25422.1
International Mouse Knockout Project Status	Fkbp10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006274	VEGA Gene Model | MGI Sequence Detail	9128	C57BL/6J
transcript	OTTMUST00000014190	VEGA | MGI Sequence Detail	2584	Not Applicable
polypeptide	OTTMUSP00000006589	VEGA | MGI Sequence Detail	581	Not Applicable

All sequences(42) RefSeq(4) UniProt(4)

Polymorphisms

RFLP(2) : SNPs(24 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR018247	EF-Hand 1, calcium-binding site
InterPro	IPR002048	EF-hand domain
InterPro	IPR011992	EF-hand-like domain
InterPro	IPR023566	Peptidyl-prolyl cis-trans isomerase, FKBP-type
InterPro	IPR001179	Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
Protein Ontology	PR:000007532	peptidyl-prolyl cis-trans isomerase FKBP10

References

(Earliest) J:15604 Simek SL, et al., Sequence and localization of a novel FK506-binding protein to mouse chromosome 11. Genomics. 1993 Nov;18(2):407-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)

Other accession IDs

MGD-MRK-28060, MGD-MRK-9809, MGI:2144131, MGI:95540