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Fkbp10
Gene Detail
 Symbol
Name
ID
Fkbp10
FK506 binding protein 10
MGI:104769
Synonyms 65kDa, Fkbp1-rs, Fkbp6, FKBP65, Fkbp-rs1
Feature Type protein coding gene
Genetic Map
Chromosome 11
63.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(14)
Sequence Map
Chr11:100415697-100424824 bp, + strand
From VEGA annotation of GRCm38

  9128 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7718  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fkbp10

Human
homologs
Human Homolog FKBP10, FK506 binding protein 10, 65 kDa
NCBI Gene ID 60681
neXtProt AC  NX_Q96AY3
Human Synonyms  FKBP65, hFKBP65, OI11, OI6, PPIASE
Human Chr (Location)  17q21.2; chr17:41812262-41823217 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FKBP10
Alleles
and
phenotypes
All alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process chaperone-mediated protein folding, protein folding, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane
Function calcium ion binding, FK506 binding, ...
External Resources: FuncBase
Expression
cDNA source data(106)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(106) cDNA(106)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000006274 (Evidence)
Ensembl Gene ModelENSMUSG00000001555 (Evidence)
Entrez Gene14230 (Evidence)
UniGene3894
DFCITC1572591
DoTSDT.91358033
NIA Mouse Gene IndexU013338
EC5.2.1.8
Consensus CDS ProjectCCDS25422.1
International Mouse Knockout Project StatusFkbp10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006274 VEGA Gene Model | MGI Sequence Detail 9128 C57BL/6J ±  kb
transcript OTTMUST00000014190 VEGA | MGI Sequence Detail 2584 Not Applicable 
polypeptide OTTMUSP00000006589 VEGA | MGI Sequence Detail 581 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(4) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018247 EF-Hand 1, calcium-binding site
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
InterPro IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
Protein Ontology PR:000007532 peptidyl-prolyl cis-trans isomerase FKBP10
References (Earliest) J:15604 Simek SL, et al., Sequence and localization of a novel FK506-binding protein to mouse chromosome 11. Genomics. 1993 Nov;18(2):407-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)
Other
accession IDs
MGD-MRK-28060, MGD-MRK-9809, MGI:2144131, MGI:95540

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory