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Gt(ROSA)26Sor
Gene Detail
Symbol

Name
ID
Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
MGI:104735
Synonyms
beta geo, Gtrgeo26, Gtrosa26, R26, ROSA26
Feature Type
unclassified non-coding RNA gene
Genetic Map
Chromosome 6
52.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr6:113067428-113077333 bp, - strand
From VEGA annotation of GRCm38

  9906 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Gt(ROSA)26Sor
Mutations,
alleles, and
phenotypes
All mutations/alleles(714) : Endonuclease-mediated(1) Gene trapped(185) Targeted(528)
 
Homozygous null mice have high rates of postnatal lethality, exhibit developmental defects of B cells, T cells and osteoclasts, and have defective dendritic cell cross-presentation of antigens from necrotic cells.
 
Alleles Annotated to Human Diseases(23)    Phenotype Images(29)
Expression
Literature Summary: (11 records)
Data Summary: Results (4)    Tissues (4)    Tissue x Stage Matrix (view)
Assay TypeResults
In situ reporter (knock in) 4
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(44) Genomic(3) cDNA(41)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000034748 (Evidence)
Ensembl Gene ModelENSMUSG00000086429 (Evidence)
Entrez Gene14910 (Evidence)
UniGene280950
DFCITC1603235, TC1649911, TC1771202
DoTSDT.101362999, DT.491815
NIA Mouse Gene IndexU027721
International Mouse Knockout Project StatusGt(ROSA)26Sor
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034748 VEGA Gene Model | MGI Sequence Detail 9906 C57BL/6J ±  kb
transcript OTTMUST00000088311 VEGA | MGI Sequence Detail 1181 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(59 from dbSNP Build 137)
References
(Earliest) J:14451 LaRosa GJ, et al., An early effect of retinoic acid: cloning of an mRNA (Era-1) exhibiting rapid and protein synthesis-independent induction during teratocarcinoma stem cell differentiation. Proc Natl Acad Sci U S A. 1988 Jan;85(2):329-33
(Latest) J:214075 Norrie JL, et al., Dynamics of BMP signaling in limb bud mesenchyme and polydactyly. Dev Biol. 2014 Sep 15;393(2):270-81
All references(4332)
Other
accession IDs
MGD-MRK-27098, MGI:2141626

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory