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Caml Gene Detail
Summary
  • Symbol
    Caml
  • Name
    calcium modulating ligand
  • Synonyms
    Caml
  • Feature Type
    protein coding gene
  • IDs
    MGI:104728
    NCBI Gene: 12328
  • Gene Overview
    MyGene.info: CAMLG
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55623005-55632411 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 30.06 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104728
protein coding gene Chr13:55623005-55632416 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020606
protein coding gene Chr13:55116638-55127076 (+)
A/J MGP_AJ_G0020560
protein coding gene Chr13:53083839-53092816 (+)
AKR/J MGP_AKRJ_G0020538
protein coding gene Chr13:54647887-54657129 (+)
BALB/cJ MGP_BALBcJ_G0020556
protein coding gene Chr13:53310742-53319940 (+)
C3H/HeJ MGP_C3HHeJ_G0020355
protein coding gene Chr13:54456071-54465097 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020990
protein coding gene Chr13:56777050-56786641 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018572
protein coding gene Chr13:51017667-51026010 (+)
CAST/EiJ MGP_CASTEiJ_G0019869
protein coding gene Chr13:54563870-54573774 (+)
CBA/J MGP_CBAJ_G0020315
protein coding gene Chr13:58958106-58971146 (+)
DBA/2J MGP_DBA2J_G0020438
protein coding gene Chr13:52629692-52638749 (+)
FVB/NJ MGP_FVBNJ_G0020417
protein coding gene Chr13:52100889-52110570 (+)
LP/J MGP_LPJ_G0020514
protein coding gene Chr13:55368520-55378838 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020446
protein coding gene Chr13:58416438-58426747 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021033
protein coding gene Chr13:54226065-54240698 (+)
PWK/PhJ MGP_PWKPhJ_G0019625
protein coding gene Chr13:52656095-52665516 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019452
protein coding gene Chr13:53148013-53157203 (+)
WSB/EiJ MGP_WSBEiJ_G0019931
protein coding gene Chr13:54592153-54601577 (+)



Homology
more
  • Human Ortholog
    CAMLG, calcium modulating ligand
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CAMLG, calcium modulating ligand
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CAML, GET2
  • Links
    NCBI Gene ID: 819
    neXtProt AC: NX_P49069
    UniProt: P49069

  • Chr Location
    5q31.1; chr5:134737927-134752160 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice lacking both functional copies of this gene die during early gestation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021501 Ensembl Gene Model | MGI Sequence Detail 9407 C57BL/6J ±  kb
transcript ENSMUST00000021963 Ensembl | MGI Sequence Detail 1382 Not Applicable  
polypeptide ENSMUSP00000021963 Ensembl | MGI Sequence Detail 294 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-27091, MGI:2145224
References
more
  • Summaries
    All 45
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:183110 Zane NA, et al., Essential role for CAML in follicular B cell survival and homeostasis. J Immunol. 2012 Apr 1;188(7):3009-18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory