About   Help   FAQ
Cct4 Gene Detail
Summary
  • Symbol
    Cct4
  • Name
    chaperonin containing Tcp1, subunit 4 (delta)
  • Synonyms
    2610204B21Rik, A45, Cctd, T complex protein 1, delta, TCP-1 delta
  • Feature Type
    protein coding gene
  • IDs
    MGI:104689
    NCBI Gene: 12464
  • Gene Overview
    MyGene.info: CCT4
Location & Maps
more
  • Sequence Map
    Chr11:22990519-23003780 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13262 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 14.25 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    CCT4, chaperonin containing TCP1 subunit 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCT4, chaperonin containing TCP1 subunit 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Cctd, CCT-DELTA, SRB
  • Links
    NCBI Gene ID: 10575
    neXtProt AC: NX_P50991

  • Chr Location
    2p15; chr2:61868127-61888671 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4695
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCT4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Targeted
    1
  • Genomic Mutations
    1 involving Cct4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005269 VEGA Gene Model | MGI Sequence Detail 13262 C57BL/6J ±  kb
transcript OTTMUST00000011740 VEGA | MGI Sequence Detail 2484 Not Applicable  
polypeptide OTTMUSP00000005437 VEGA | MGI Sequence Detail 539 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    46 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 1
    cDNA 26
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-27052, MGI:1914415, MGI:2144639
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 9
  • Earliest
    J:20653 Xie X, et al., Cloning and expression of a new mammalian chaperonin gene from a multipotent hematopoietic progenitor clone. Blood. 1994 Oct 1;84(7):2171-4
  • Latest
    J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/29/2016
MGI 6.06
The Jackson Laboratory