About   Help   FAQ
Cct4 Gene Detail
Summary
  • Symbol
    Cct4
  • Name
    chaperonin containing Tcp1, subunit 4 (delta)
  • Synonyms
    2610204B21Rik, A45, Cctd, T complex protein 1, delta, TCP-1 delta
  • Feature Type
    protein coding gene
  • IDs
    MGI:104689
    NCBI Gene: 12464
  • Gene Overview
    MyGene.info: CCT4
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:22990593-23003336 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 14.25 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104689
protein coding gene Chr11:22990519-23003780 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018083
protein coding gene Chr11:20705225-20718486 (+)
A/J MGP_AJ_G0018056
protein coding gene Chr11:19915621-19928882 (+)
AKR/J MGP_AKRJ_G0018020
protein coding gene Chr11:20627604-20642461 (+)
BALB/cJ MGP_BALBcJ_G0018024
protein coding gene Chr11:20051022-20064290 (+)
C3H/HeJ MGP_C3HHeJ_G0017838
protein coding gene Chr11:20504328-20517598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018476
protein coding gene Chr11:21560057-21573309 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016134
protein coding gene Chr11:18815662-18830569 (+)
CAST/EiJ MGP_CASTEiJ_G0017399
protein coding gene Chr11:20557835-20572239 (+)
CBA/J MGP_CBAJ_G0017812
protein coding gene Chr11:22516078-22529508 (+)
DBA/2J MGP_DBA2J_G0017922
protein coding gene Chr11:19846002-19859262 (+)
FVB/NJ MGP_FVBNJ_G0017914
protein coding gene Chr11:19622241-19635713 (+)
LP/J MGP_LPJ_G0017993
protein coding gene Chr11:20818762-20833410 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017940
protein coding gene Chr11:22989175-23002447 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018517
protein coding gene Chr11:20737197-20750454 (+)
PWK/PhJ MGP_PWKPhJ_G0017180
protein coding gene Chr11:19880354-19893383 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016977
protein coding gene Chr11:20477168-20491408 (+)
WSB/EiJ MGP_WSBEiJ_G0017453
protein coding gene Chr11:20362153-20375535 (+)



Homology
more
  • Human Ortholog
    CCT4, chaperonin containing TCP1 subunit 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCT4, chaperonin containing TCP1 subunit 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Cctd, CCT-DELTA, SRB
  • Links
    NCBI Gene ID: 10575
    neXtProt AC: NX_P50991
    UniProt: P50991

  • Chr Location
    2p15; chr2:61868127-61888671 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4695
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCT4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12464 NCBI Gene Model | MGI Sequence Detail 12744 C57BL/6J ±  kb
transcript NM_009837 RefSeq | MGI Sequence Detail 1966 129/Sv  
polypeptide P80315 UniProt | EBI | MGI Sequence Detail 539 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000005152 T-complex protein 1 subunit delta
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain superfamily
    IPR027413 GroEL-like equatorial domain superfamily
    IPR012717 T-complex protein 1, delta subunit
    IPR027410 TCP-1-like chaperonin intermediate domain superfamily
Molecular
Reagents
less
  • All nucleic 29
    Genomic 1
    cDNA 27
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-27052, MGI:1914415, MGI:2144639
References
more
  • Summaries
    All 49
    Developmental Gene Expression 1
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory