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Prpf39 Gene Detail
Summary
  • Symbol
    Prpf39
  • Name
    pre-mRNA processing factor 39
  • Synonyms
    MGC:37077, Srcs1
  • Feature Type
    protein coding gene
  • IDs
    MGI:104602
    NCBI Gene: 328110
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:65036333-65063386 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 27.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    109 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104602
protein coding gene Chr12:65036309-65063386 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019778
protein coding gene Chr12:64515693-64542741 (+)
A/J MGP_AJ_G0019737
protein coding gene Chr12:62134044-62161422 (+)
AKR/J MGP_AKRJ_G0019712
protein coding gene Chr12:64113728-64140780 (+)
BALB/cJ MGP_BALBcJ_G0019717
protein coding gene Chr12:62575747-62602838 (+)
C3H/HeJ MGP_C3HHeJ_G0019522
protein coding gene Chr12:64454945-64486885 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020169
protein coding gene Chr12:66552541-66579965 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017789
protein coding gene Chr12:59950196-59977756 (+)
CAST/EiJ MGP_CASTEiJ_G0019074
protein coding gene Chr12:59162116-59193589 (+)
CBA/J MGP_CBAJ_G0019491
protein coding gene Chr12:68976420-69006185 (+)
DBA/2J MGP_DBA2J_G0019607
protein coding gene Chr12:62062427-62089528 (+)
FVB/NJ MGP_FVBNJ_G0019595
protein coding gene Chr12:61088509-61116000 (+)
LP/J MGP_LPJ_G0019679
protein coding gene Chr12:64534775-64564119 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019633
protein coding gene Chr12:71840069-71873288 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020203
protein coding gene Chr12:63501105-63528134 (+)
PWK/PhJ MGP_PWKPhJ_G0018840
protein coding gene Chr12:56334938-56362534 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018634
protein coding gene Chr12:57823219-57850989 (+)
WSB/EiJ MGP_WSBEiJ_G0019125
protein coding gene Chr12:64032574-64059612 (+)



Homology
more
  • Human Ortholog
    PRPF39, pre-mRNA processing factor 39
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PRPF39, pre-mRNA processing factor 39
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55015
    neXtProt AC: NX_Q86UA1
    UniProt: Q86UA1

  • Chr Location
    14q21.2; chr14:45084099-45115601 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035597 Ensembl Gene Model | MGI Sequence Detail 27054 C57BL/6J ±  kb
transcript ENSMUST00000120580 Ensembl | MGI Sequence Detail 4069 Not Applicable  
polypeptide ENSMUSP00000112953 Ensembl | MGI Sequence Detail 665 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-26038
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:22534 Frankfort BJ, et al., Identification of novel cellular genes transcriptionally suppressed by v-src. Biochem Biophys Res Commun. 1995 Jan 26;206(3):916-26
  • Latest
    J:256883 Zhou J, et al., Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory