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Xcl1
Gene Detail
 Symbol
Name
ID
Xcl1
chemokine (C motif) ligand 1
MGI:104593
Synonyms ATAC, Lptn, LTN, lymphotactin, SCM-1, SCM-1a, Scyc1
Feature Type protein coding gene
Genetic Map
Chromosome 1
72.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr1:164931644-164935527 bp, - strand
From VEGA annotation of GRCm38

  3884 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2250  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 2 cattle; 1 dog

Protein SuperFamily: small inducible chemokine, C/CC types
Gene Tree: Xcl1

Human
homologs
Human Homolog XCL1, chemokine (C motif) ligand 1
NCBI Gene ID 6375
neXtProt AC  NX_P47992
Human Synonyms  ATAC, LPTN, LTN, SCM1, SCM-1, SCM-1a, SCM1A, SCYC1
Human Chr (Location)  1q23; chr1:168576473-168582077 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
 
Mice homozygous for a knock-out allele exhibit decreased stimulated cytotoxic T cell cytolysis.
 
Interactions
Xcl1 interacts with 22 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (53 annotations)
Process cell-cell signaling, cellular response to interleukin-4, ...
Component cell, cytosol, ...
Function chemokine activity, chemokine receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (15)    Images (2)
Theiler Stages: 23
Assay TypeResults
RNA in situ 24
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026875 (Evidence)
Ensembl Gene ModelENSMUSG00000026573 (Evidence)
Entrez Gene16963 (Evidence)
UniGene190
DFCITC1586561
DoTSDT.487593
NIA Mouse Gene IndexU021985
Consensus CDS ProjectCCDS15438.1
International Mouse Knockout Project StatusXcl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026875 VEGA Gene Model | MGI Sequence Detail 3884 C57BL/6J ±  kb
transcript OTTMUST00000066472 VEGA | MGI Sequence Detail 523 Not Applicable 
polypeptide OTTMUSP00000033314 VEGA | MGI Sequence Detail 114 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008105 C chemokine ligand 1
InterPro IPR001811 Chemokine interleukin-8-like domain
Protein Ontology PR:000002140 lymphotactin
References (Earliest) J:29507 Kelner GS, et al., Lymphotactin: a cytokine that represents a new class of chemokine. Science. 1994 Nov 25;266(5189):1395-9
(Latest) J:211295 Milicevic NM, et al., Aberrant Tissue Positioning of Metallophilic Macrophages in the Thymus of XCL1-Deficient Mice. Anat Rec (Hoboken). 2014 Aug;297(8):1472-7
All references(51)
Other
accession IDs
MGD-MRK-26027, MGI:2138317

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory