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Myef2 Gene Detail
Summary
  • Symbol
    Myef2
  • Name
    myelin basic protein expression factor 2, repressor
  • Synonyms
    mKIAA1341
  • Feature Type
    protein coding gene
  • IDs
    MGI:104592
    NCBI Gene: 17876
Location & Maps
more
  • Sequence Map
    Chr2:125084628-125123661 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39034 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 61.16 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    MYEF2, myelin expression factor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYEF2, myelin expression factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HsT18564, MEF-2, MST156, MSTP156, myEF-2
  • Links
    NCBI Gene ID: 50804
    neXtProt AC: NX_Q9P2K5

  • Chr Location
    15q21.1; chr15:48139428-48178400 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 69079
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: MYEF2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    32
  • Chemically induced (other)
    1
  • Gene trapped
    27
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Myef2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015333 VEGA Gene Model | MGI Sequence Detail 39034 C57BL/6J ±  kb
transcript OTTMUST00000036338 VEGA | MGI Sequence Detail 2071 Not Applicable  
polypeptide OTTMUSP00000043530 VEGA | MGI Sequence Detail 591 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    144 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010815 myelin expression factor 2
Molecular
Reagents
less
  • All nucleic 86
    cDNA 85
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-26026
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:25637 Haas S, et al., Identification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein gene. J Biol Chem. 1995 May 26;270(21):12503-10
  • Latest
    J:188791 van Riel B, et al., A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Mol Cell Biol. 2012 Oct;32(19):3814-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory