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Gnb4 Gene Detail
Summary
  • Symbol
    Gnb4
  • Name
    guanine nucleotide binding protein (G protein), beta 4
  • Synonyms
    6720453A21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:104581
    NCBI Gene: 14696
  • Gene Overview
    MyGene.info: GNB4
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:32580332-32616535 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 15.78 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    269 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104581
protein coding gene Chr3:32580332-32616585 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027140
protein coding gene Chr3:30195824-30233532 (-)
A/J MGP_AJ_G0027100
protein coding gene Chr3:29767903-29804492 (-)
AKR/J MGP_AKRJ_G0027069
protein coding gene Chr3:30225210-30261146 (-)
BALB/cJ MGP_BALBcJ_G0027112
protein coding gene Chr3:29415436-29451458 (-)
C3H/HeJ MGP_C3HHeJ_G0026855
protein coding gene Chr3:30250283-30290892 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027558
protein coding gene Chr3:31694770-31733081 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024919
protein coding gene Chr3:27594910-27632558 (-)
CAST/EiJ MGP_CASTEiJ_G0026308
protein coding gene Chr3:30114993-30150732 (-)
CBA/J MGP_CBAJ_G0026832
protein coding gene Chr3:32543339-32583339 (-)
DBA/2J MGP_DBA2J_G0026966
protein coding gene Chr3:29234769-29270622 (-)
FVB/NJ MGP_FVBNJ_G0026934
protein coding gene Chr3:28694172-28730395 (-)
LP/J MGP_LPJ_G0027078
protein coding gene Chr3:30957655-30997915 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026954
protein coding gene Chr3:35050806-35087365 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027617
protein coding gene Chr3:30019731-30056815 (-)
PWK/PhJ MGP_PWKPhJ_G0026041
protein coding gene Chr3:28777571-28814102 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025853
protein coding gene Chr3:29431475-29467983 (-)
WSB/EiJ MGP_WSBEiJ_G0026382
protein coding gene Chr3:30039371-30076370 (-)



Homology
more
  • Human Ortholog
    GNB4, G protein subunit beta 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GNB4, G protein subunit beta 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CMTD1F
  • Links
    NCBI Gene ID: 59345
    neXtProt AC: NX_Q9HAV0
    UniProt: Q9HAV0

  • Chr Location
    3q26.33; chr3:179396088-179451583 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human GNB4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14696 NCBI Gene Model | MGI Sequence Detail 36204 C57BL/6J ±  kb
transcript NM_001348104 RefSeq | MGI Sequence Detail 8008 C57BL/6  
polypeptide P29387 UniProt | EBI | MGI Sequence Detail 340 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 21
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-26015, MGI:1925135
References
more
  • Summaries
    All 44
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:10436 Danciger M, et al., The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8. Genomics. 1990 Mar;6(3):428-35
  • Latest
    J:242591 Guo Y, et al., Gbeta2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex. Cereb Cortex. 2017 Jun 01;27(6):3414-3426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory