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Slc23a3 Gene Detail
Summary
  • Symbol
    Slc23a3
  • Name
    solute carrier family 23 (nucleobase transporters), member 3
  • Synonyms
    SVCT3, Yspl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:104516
    NCBI Gene: 22626
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:75102185-75110534 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 38.60 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    530 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104516
 protein coding gene Chr1:75102185-75112113 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016170
 protein coding gene Chr1:75684125-75692474 (-)
A/J MGP_AJ_G0016153
 protein coding gene Chr1:73046342-73054696 (-)
AKR/J MGP_AKRJ_G0016110
 protein coding gene Chr1:75074819-75083172 (-)
BALB/cJ MGP_BALBcJ_G0016108
 protein coding gene Chr1:73109559-73117908 (-)
C3H/HeJ MGP_C3HHeJ_G0015939
 protein coding gene Chr1:75406141-75414495 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016561
 protein coding gene Chr1:78638332-78646681 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014282
 protein coding gene Chr1:68608632-68617518 (-)
CAST/EiJ MGP_CASTEiJ_G0015523
 protein coding gene Chr1:74740860-74751143 (-)
CBA/J MGP_CBAJ_G0015912
 protein coding gene Chr1:81191871-81200225 (-)
DBA/2J MGP_DBA2J_G0016013
 protein coding gene Chr1:72366212-72374561 (-)
FVB/NJ MGP_FVBNJ_G0016016
 protein coding gene Chr1:71562608-71570990 (-)
LP/J MGP_LPJ_G0016085
 protein coding gene Chr1:76810289-76818638 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016036
 protein coding gene Chr1:84552997-84561351 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016608
 protein coding gene Chr1:75143209-75151558 (-)
PWK/PhJ MGP_PWKPhJ_G0015310
 protein coding gene Chr1:71833883-71842550 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015088
 protein coding gene Chr1:74505734-74514160 (-)
WSB/EiJ MGP_WSBEiJ_G0015585
 protein coding gene Chr1:74956630-74964982 (-)



Homology
more
  • Human Ortholog
    SLC23A3, solute carrier family 23 member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC23A3, solute carrier family 23 member 3
  • Synonyms
    E2BP3, SVCT3, Yspl1
  • Links
    NCBI Gene ID: 151295
    UniProt: Q6PIS1

  • Chr Location
    2q35; chr2:219161465-219170095 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    762
  • Tissues
    53
  • cDNA Data
    17
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026205 Ensembl Gene Model | MGI Sequence Detail 8350 C57BL/6J ±  kb
    transcript ENSMUST00000027405 Ensembl | MGI Sequence Detail 2059 Not Applicable  
    polypeptide ENSMUSP00000027405 Ensembl | MGI Sequence Detail 611 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      Genomic 1
      cDNA 17
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-25947
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 1
      Phenotypes 25
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory