|Human Homolog||TNFSF4, tumor necrosis factor (ligand) superfamily, member 4|
|NCBI Gene ID||7292|
|Human Synonyms||CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1|
|Human Chr (Location)||1q25; chr1:173183731-173207332 (-) GRCh38|
|Disease Associations||(1) Diseases Associated with Human TNFSF4|
Homozygous inactivation of this gene leads to an impaired contact hypersensitivity response due to defects in T cell priming and cytokine production. Homozygosity for a null allele confers resistance to autoimmune diabetes development in nonobese diabetic mice.
|Process||acute inflammatory response, blood vessel development, ...|
|Component||cell surface, extracellular space, ...|
|Function||cytokine activity, tumor necrosis factor receptor binding, ...|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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