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Cebpd
Gene Detail
 Symbol
Name
ID
Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
MGI:103573
BioType Conflict
Feature Type protein coding gene
Genetic Map
Chromosome 16
10.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr16:15887286-15888466 bp, + strand
From Ensembl annotation of GRCm38

  1181 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3808  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: CCAAT/enhancer-binding protein
Gene Tree: Cebpd

Human
homologs
Human Homolog CEBPD, CCAAT/enhancer binding protein (C/EBP), delta
NCBI Gene ID 1052
neXtProt AC  NX_P49716
Human Synonyms  C/EBP-delta, CELF, CRP3, NF-IL6-beta
Human Chr (Location)  8p11.2-p11.1; chr8:47736914-47738164 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
 
Mice homozygous for a knock-out allele are viable and healthy and perform normally on several behavioral tasks, but display enhanced contextual fear conditioning. Mice homozygous for a second knock-out allele exhibit nearly normal or only slightly impaired adipocyte differentiation.
 
Interactions
Cebpd interacts with 39 markers (Mir22, Mir98, Mir103-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process fat cell differentiation, hematopoietic progenitor cell differentiation, ...
Component nucleus
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (18 records)
Data Summary: Results (183)    Tissues (146)    Images (12)
Theiler Stages: 1, 2, 9, 13, 17, 20, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
Immunohistochemistry 6
RNA in situ 118
Northern blot 35
Western blot 8
RT-PCR 16
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) Genomic(5) cDNA(41) Primer pair(1) Other(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000071637 (Evidence)
Entrez Gene12609 (Evidence)
UniGene347407
DFCITC1578875
DoTSDT.101364847, DT.110721652, DT.531992, DT.94349867
NIA Mouse Gene IndexU016849
International Mouse Knockout Project StatusCebpd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071637 Ensembl Gene Model | MGI Sequence Detail 1181 C57BL/6J ±  kb
transcript ENSMUST00000096232 Ensembl | MGI Sequence Detail 1180 Not Applicable 
polypeptide Q00322 UniProt | EBI | MGI Sequence Detail 268 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(4)
Polymorphisms RFLP(4) : SNPs within 2kb(0 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR016468 CCAAT/enhancer-binding
Protein Ontology PR:000005309 CCAAT/enhancer-binding protein delta
Graphical View of Protein Domain Structure
References (Earliest) J:23758 Cao Z, et al., Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 1991 Sep;5(9):1538-52
(Latest) J:211975 Ko CY, et al., Glycogen synthase kinase-3beta-mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promotes migration and activation of microglia/macrophages. Neurobiol Aging. 2014 Jan;35(1):24-34
All references(98)
Other
accession IDs
MGD-MRK-24458

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory