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Ptprk Gene Detail
Summary
  • Symbol
    Ptprk
  • Name
    protein tyrosine phosphatase, receptor type, K
  • Synonyms
    PTPk, RPTPkappa
  • Feature Type
    protein coding gene
  • IDs
    MGI:103310
    NCBI Gene: 19272
  • Gene Overview
    MyGene.info: PTPRK
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:28074820-28597397 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 15.06 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3513 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103310
protein coding gene Chr10:28074481-28597397 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017106
protein coding gene Chr10:26186237-26735127 (+)
A/J MGP_AJ_G0017083
protein coding gene Chr10:25396516-25925219 (+)
AKR/J MGP_AKRJ_G0017043
protein coding gene Chr10:25808326-26340426 (+)
BALB/cJ MGP_BALBcJ_G0017046
protein coding gene Chr10:25517112-26037916 (+)
C3H/HeJ MGP_C3HHeJ_G0016866
protein coding gene Chr10:26062187-26589425 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017504
protein coding gene Chr10:26986532-27536630 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015202
protein coding gene Chr10:23951355-24461908 (+)
CAST/EiJ MGP_CASTEiJ_G0016445
protein coding gene Chr10:26075309-26631506 (+)
CBA/J MGP_CBAJ_G0016840
protein coding gene Chr10:28296143-28866395 (+)
DBA/2J MGP_DBA2J_G0016945
protein coding gene Chr10:25107101-25633934 (+)
FVB/NJ MGP_FVBNJ_G0016940
protein coding gene Chr10:24762559-25280886 (+)
LP/J MGP_LPJ_G0017022
protein coding gene Chr10:26182450-26721403 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016970
protein coding gene Chr10:28389057-28973008 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017540
protein coding gene Chr10:25705093-26240707 (+)
PWK/PhJ MGP_PWKPhJ_G0016227
protein coding gene Chr10:24908229-25429001 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016011
protein coding gene Chr10:25571684-26110595 (+)
WSB/EiJ MGP_WSBEiJ_G0016508
protein coding gene Chr10:25839876-26374165 (+)



Homology
more
  • Human Ortholog
    PTPRK, protein tyrosine phosphatase, receptor type K
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PTPRK, protein tyrosine phosphatase, receptor type K
    Orthology source: HomoloGene, HGNC
  • Synonyms
    R-PTP-kappa
  • Links
    NCBI Gene ID: 5796
    neXtProt AC: NX_Q15262
    UniProt: Q15262

  • Chr Location
    6q22.33; chr6:127968779-128520847 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019889 Ensembl Gene Model | MGI Sequence Detail 522578 C57BL/6J ±  kb
transcript ENSMUST00000218276 Ensembl | MGI Sequence Detail 4754 Not Applicable  
polypeptide ENSMUSP00000151866 Ensembl | MGI Sequence Detail 1471 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 79
    cDNA 75
    Primer pair 2
    Other 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-24194, MGI:2143696
References
more
  • Summaries
    All 48
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory