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Ptprk Gene Detail
Summary
  • Symbol
    Ptprk
  • Name
    protein tyrosine phosphatase, receptor type, K
  • Synonyms
    PTPk, RPTPkappa
  • Feature Type
    protein coding gene
  • IDs
    MGI:103310
    NCBI Gene: 19272
  • Gene Overview
    MyGene.info: PTPRK
Location & Maps
more
  • Sequence Map
    Chr10:28074820-28597397 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      522578 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 15.06 cM
  • Mapping Data
    8 experiments
Homology
more
  • Human Ortholog
    PTPRK, protein tyrosine phosphatase, receptor type K
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PTPRK, protein tyrosine phosphatase, receptor type K
    Orthology source: HomoloGene
  • Synonyms
    R-PTP-kappa
  • Links
    NCBI Gene ID: 5796
    neXtProt AC: NX_Q15262

  • Chr Location
    6q22.2-q22.3; chr6:127968779-128520847 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    55
  • Chemically induced (other)
    1
  • Gene trapped
    54
  • Genomic Mutations
    1 involving Ptprk
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019889 Ensembl Gene Model | MGI Sequence Detail 522578 C57BL/6J ±  kb
transcript ENSMUST00000166468 Ensembl | MGI Sequence Detail 6177 Not Applicable  
polypeptide ENSMUSP00000126279 Ensembl | MGI Sequence Detail 1457 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    3513 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 73
    Primer pair 2
    Other 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-24194, MGI:2143696
References
more
  • Summaries
    All 38
    Developmental Gene Expression 11
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:25687 Jiang YP, et al., Cloning and characterization of R-PTP-kappa, a new member of the receptor protein tyrosine phosphatase family with a proteolytically cleaved cellular adhesion molecule-like extracellular region. Mol Cell Biol. 1993 May;13(5):2942-51
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory