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Rab19 Gene Detail
Summary
  • Symbol
    Rab19
  • Name
    RAB19, member RAS oncogene family
  • Feature Type
    protein coding gene
  • IDs
    MGI:103292
    NCBI Gene: 19331
Location & Maps
more
  • Sequence Map
    Chr6:39381175-39390380 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9206 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 18.16 cM, cytoband B1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RAB19, RAB19, member RAS oncogene family
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RAB19, RAB19, member RAS oncogene family
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RAB19B
  • Links
    NCBI Gene ID: 401409
    neXtProt AC: NX_A4D1S5

  • Chr Location
    7q34; chr7:140403822-140426878 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    12
  • Gene trapped
    8
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022161 VEGA Gene Model | MGI Sequence Detail 9206 C57BL/6J ±  kb
transcript OTTMUST00000052624 VEGA | MGI Sequence Detail 1575 Not Applicable  
polypeptide OTTMUSP00000024975 VEGA | MGI Sequence Detail 217 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    14 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000013590 ras-related protein Rab-19
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-24174
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory