About   Help   FAQ
Polr1c
Gene Detail
Symbol

Name
ID
Polr1c
polymerase (RNA) I polypeptide C
MGI:103288
Synonyms
40kDa, RPA40, Rpo1-1
Feature Type
protein coding gene
Genetic Map
Chromosome 17
22.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:46243920-46248054 bp, - strand
From VEGA annotation of GRCm38

  4135 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3586  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: POLR1C
Protein SuperFamily: DNA-directed RNA polymerase 40K chain
Gene Tree: Polr1c

Human
homologs
POLR1C, polymerase (RNA) I polypeptide C, 30kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9533
neXtProt AC: NX_O15160

Human Synonyms: RPA39, RPA40, RPA5, RPAC1, TCS3

Human Chr (Location): 6p21.1; chr6:43517039-43550984 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human POLR1C

Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(17) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr1c interacts with 31 markers (Mir103-1, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(98)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA POLR1C ; Xenbase polr1c ; ZFIN polr1c    NEW 
Molecular
reagents
All nucleic(98) cDNA(98)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000028872 (Evidence)
Ensembl Gene Model ENSMUSG00000067148 (Evidence)
Entrez Gene 20016 (Evidence)
UniGene 3458
NIA Mouse Gene Index U037850
Consensus CDS Project CCDS37632.1
International Mouse Phenotyping Consortium Status Polr1c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028872 VEGA Gene Model | MGI Sequence Detail 4135 C57BL/6J ±  kb
transcript OTTMUST00000071518 VEGA | MGI Sequence Detail 1314 Not Applicable 
polypeptide OTTMUSP00000036652 VEGA | MGI Sequence Detail 346 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(2) UniProt(6)
Polymorphisms
SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
InterPro IPR011262 DNA-directed RNA polymerase, insert domain
InterPro IPR009025 DNA-directed RNA polymerase, RBP11-like
InterPro IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type
Protein Ontology PR:000012984 DNA-directed RNA polymerases I and III subunit RPAC1
References
(Earliest) J:21850 Song CZ, et al., High conservation of subunit composition of RNA polymerase I(A) between yeast and mouse and the molecular cloning of mouse RNA polymerase I 40-kDa subunit RPA40. J Biol Chem. 1994 Oct 28;269(43):26976-81
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGD-MRK-24170, MGI:2146755, MGI:2146784, MGI:2146961

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/20/2015
MGI 5.22
The Jackson Laboratory