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Rpia
Gene Detail
Symbol

Name
ID
Rpia
ribose 5-phosphate isomerase A
MGI:103254
Feature Type
protein coding gene
Genetic Map
Chromosome 6
32.06 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:70765720-70792232 bp, - strand
From VEGA annotation of GRCm38

  26513 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6943  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RPIA
Gene Tree: Rpia

Human
homologs
RPIA, ribose 5-phosphate isomerase A
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 22934
neXtProt AC: NX_P49247

Human Synonyms: RPI, RPIAD

Human Chr (Location): 2p11.2; chr2:88691648-88750935 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RPIA

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from APF )
Interactions
Rpia interacts with 176 markers (Mir7-1, Mir17, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process pentose-phosphate shunt, pentose-phosphate shunt, non-oxidative branch, ...
Component intracellular membrane-bounded organelle
Function carbohydrate binding, isomerase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(31)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rpia    NEW 
Molecular
reagents
All nucleic(35) Genomic(4) cDNA(31)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000022844 (Evidence)
Ensembl Gene Model ENSMUSG00000053604 (Evidence)
Entrez Gene 19895 (Evidence)
UniGene 17905
DFCI TC1581273
DoTS DT.491986
NIA Mouse Gene Index U027445
EC 5.3.1.6
Consensus CDS Project CCDS39504.1
International Mouse Phenotyping Consortium Status Rpia
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022844 VEGA Gene Model | MGI Sequence Detail 26513 C57BL/6J ±  kb
transcript OTTMUST00000054914 VEGA | MGI Sequence Detail 1829 Not Applicable 
polypeptide OTTMUSP00000026232 VEGA | MGI Sequence Detail 303 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(182 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004788 Ribose 5-phosphate isomerase, type A
InterPro IPR020672 Ribose-5-phosphate isomerase, type A, subgroup
Protein Ontology PR:000014186 ribose-5-phosphate isomerase
References
(Earliest) J:25086 Apel TW, et al., The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa. Gene. 1995 Apr 24;156(2):191-7
(Latest) J:218247 Cossette SM, et al., Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 2014;4(1):48-61
All references(30)
Other
accession IDs
MGD-MRK-24130

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory