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Calm3 Gene Detail
Summary
  • Symbol
    Calm3
  • Name
    calmodulin 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:103249
    NCBI Gene: 12315
  • Alliance
    gene page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:16649304-16657957 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.15 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103249
 protein coding gene Chr7:16649304-16658039 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031723
 protein coding gene Chr7:14682452-14692110 (-)
A/J MGP_AJ_G0031695
 protein coding gene Chr7:14396569-14405301 (-)
AKR/J MGP_AKRJ_G0031620
 protein coding gene Chr7:14738057-14746815 (-)
BALB/cJ MGP_BALBcJ_G0031702
 protein coding gene Chr7:14504479-14513227 (-)
C3H/HeJ MGP_C3HHeJ_G0031424
 protein coding gene Chr7:14922406-14931068 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032168
 protein coding gene Chr7:15411143-15419751 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029247
 protein coding gene Chr7:15933344-15942000 (-)
CAST/EiJ MGP_CASTEiJ_G0030775
 protein coding gene Chr7:11700765-11710171 (-)
CBA/J MGP_CBAJ_G0031383
 protein coding gene Chr7:15927926-15943246 (-)
DBA/2J MGP_DBA2J_G0031539
 protein coding gene Chr7:14288463-14297861 (-)
FVB/NJ MGP_FVBNJ_G0031495
 protein coding gene Chr7:14188882-14198133 (-)
LP/J MGP_LPJ_G0031624
 protein coding gene Chr7:14917733-14926455 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031530
 protein coding gene Chr7:15847676-15858323 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032197
 protein coding gene Chr7:14516088-14525543 (-)
PWK/PhJ MGP_PWKPhJ_G0030499
 protein coding gene Chr7:11808585-11817811 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030326
 protein coding gene Chr7:9438734-9447386 (-)
WSB/EiJ MGP_WSBEiJ_G0030872
 protein coding gene Chr7:14582916-14591703 (-)



Homology
more
  • Human Ortholog
    CALM3, calmodulin 3
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALM3, calmodulin 3
  • Synonyms
    CALM, CaM, CAM1, CAM2, CAMB, CaMIII, CPVT6, HEL-S-72, LQT16, PHKD, PHKD3
  • Links
    NCBI Gene ID: 808
    neXtProt AC: NX_P0DP23, NX_P0DP24, NX_P0DP25
    UniProt: P0DP25

  • Chr Location
    19q13.32; chr19:46601074-46610782 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CALM3 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    124
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    811
  • Tissues
    98
  • cDNA Data
    291
  • Literature Summary
    8
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 12315 NCBI Gene Model | MGI Sequence Detail 8654 C57BL/6J ±  kb
transcript NM_007590 RefSeq | MGI Sequence Detail 2233 ZRU/MplStud  
polypeptide P0DP28 UniProt | EBI | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 296
    Genomic 1
    cDNA 292
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-24125, MGI:2142387
References
more
  • Summaries
    All 50
    Developmental Gene Expression 8
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:19936 Bender PK, et al., The abundance of calmodulin mRNAs is regulated in phosphorylase kinase-deficient skeletal muscle. J Biol Chem. 1988 Jul 15;263(20):9733-7
  • Latest
    J:298146 Bae B, et al., Elimination of Calm1 long 3'-UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice. RNA. 2020 Oct;26(10):1414-1430
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory