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Meox1
Gene Detail
Symbol

Name
ID
Meox1
mesenchyme homeobox 1
MGI:103220
Synonyms
D330041M02Rik, Mox1, Mox-1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
65.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr11:101877510-101894374 bp, - strand
From VEGA annotation of GRCm38

  16865 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3326  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: MEOX1
Gene Tree: Meox1

Human
homologs
MEOX1, mesenchyme homeobox 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4222
neXtProt AC: NX_P50221

Human Synonyms: KFS2, MOX1

Human Chr (Location): 17q21; chr17:43640389-43661954 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MEOX1

Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Gene trapped(16) Targeted(3) Transgenic(1)
Genomic Mutations involving Meox1 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a targeted null mutation exhibit hemi-vertebrae, and rib, vertebral, and cranial-vertebral fusions, but are viable and fertile.
 
Interactions
Meox1 interacts with 171 markers (Mir15a, Mir17, Mir19a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (133 records)
Data Summary: Results (310)    Tissues (163)    Images (112)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 51
RNA in situ 245
Northern blot 6
RT-PCR 8
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA MEOX1 ZFIN meox1    NEW 
Molecular
reagents
All nucleic(41) Genomic(1) cDNA(26) Primer pair(5) Other(9)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000002088 (Evidence)
Ensembl Gene Model ENSMUSG00000001493 (Evidence)
Entrez Gene 17285 (Evidence)
UniGene 3404
DFCI TC1581674
DoTS DT.487603
NIA Mouse Gene Index U033458
Consensus CDS Project CCDS25480.1
International Mouse Phenotyping Consortium Status Meox1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002088 VEGA Gene Model | MGI Sequence Detail 16865 C57BL/6J ±  kb
transcript OTTMUST00000004226 VEGA | MGI Sequence Detail 2228 Not Applicable 
polypeptide OTTMUSP00000002010 VEGA | MGI Sequence Detail 253 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms
All PCR and RFLP(7) : PCR(2) RFLP(5) SNPs within 2kb(110 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000010322 homeobox protein MOX-1
References
(Earliest) J:3682 Candia AF, et al., Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development. 1992 Dec;116(4):1123-36
(Latest) J:222399 Kitazawa T, et al., Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process. Dev Biol. 2015 Jun 15;402(2):162-74
All references(173)
Other
accession IDs
MGD-MRK-12394, MGD-MRK-12396, MGD-MRK-24090, MGI:2144139

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory