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Rn7sk Gene Detail
Summary
  • Symbol
    Rn7sk
  • Name
    RNA, 7SK, nuclear
  • Feature Type
    snRNA gene
  • IDs
    MGI:103186
    NCBI Gene: 19817
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr9:78082585-78082915 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 43.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103186
 snRNA gene Chr9:78082584-78082915 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RN7SK, RNA component of 7SK nuclear ribonucleoprotein
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RN7SK, RNA component of 7SK nuclear ribonucleoprotein
  • Synonyms
    7SK
  • Links
    NCBI Gene ID: 125050

  • Chr Location
    6p12.2; chr6:52995620-52995951 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Rn7sk
  • Find Mice (IMSR)
    2 strains or lines available
Mice homozygous for a null allele exhibit incomplete preweaning lethality. Mice homozygous for a conditional allele activated in epidermal cells exhibit reduced epidermis cellularity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    22
  • Tissues
    22
  • cDNA Data
    2
  • Literature Summary
    4
  • Other Mouse Links
    GEO
Sequences &
Gene Models
less
  • All Sequences
    6
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00002076161 Ensembl Gene Model | MGI Sequence Detail 331 C57BL/6J ±  kb
transcript ENSMUST00020183253 Ensembl | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 2
    Primer pair 1
Other
Accession IDs
less
MGD-MRK-24054
References
more
  • Summaries
    All 18
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:331226 Bandiera R, et al., RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin. Nat Commun. 2021 Oct 7;12(1):5864
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory