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Tcf19 Gene Detail
Summary
  • Symbol
    Tcf19
  • Name
    transcription factor 19
  • Synonyms
    5730403J10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:103180
    NCBI Gene: 106795
  • Gene Overview
    MyGene.info: TCF19
Location & Maps
more
  • Sequence Map
    Chr17:35512734-35516824 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4091 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.69 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TCF19, transcription factor 19
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TCF19, transcription factor 19
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SC1, TCF-19
  • Links
    NCBI Gene ID: 6941
    neXtProt AC: NX_Q9Y242

  • Chr Location
    6p21.3; chr6:31158526-31164215 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5156
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TCF19
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    1 involving Tcf19
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034281 VEGA Gene Model | MGI Sequence Detail 4091 C57BL/6J ±  kb
transcript OTTMUST00000087143 VEGA | MGI Sequence Detail 1665 Not Applicable  
polypeptide OTTMUSP00000047263 VEGA | MGI Sequence Detail 263 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016178 transcription factor 19
  • InterPro Domains
    IPR000253 Forkhead-associated (FHA) domain
    IPR008984 SMAD/FHA domain
Molecular
Reagents
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  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-24048, MGI:1913880, MGI:2147068
References
more
  • Summaries
    All 33
    Developmental Gene Expression 8
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:19352 Kanki JP, et al., The molecular cloning and characterization of potential chick DM-GRASP homologs in zebrafish and mouse. J Neurobiol. 1994 Jul;25(7):831-45
  • Latest
    J:203187 Krautkramer KA, et al., Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 beta-cell line. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E600-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory