About   Help   FAQ
Gabrg1 Gene Detail
Summary
  • Symbol
    Gabrg1
  • Name
    gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
  • Synonyms
    GabaA
  • Feature Type
    protein coding gene
  • IDs
    MGI:103156
    NCBI Gene: 14405
  • Gene Overview
    MyGene.info: GABRG1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:70751047-70842617 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 37.43 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    263 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103156
protein coding gene Chr5:70751047-70842617 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029605
protein coding gene Chr5:70620851-70704676 (-)
A/J MGP_AJ_G0029573
protein coding gene Chr5:67984613-68071489 (-)
AKR/J MGP_AKRJ_G0029521
protein coding gene Chr5:70164823-70253152 (-)
BALB/cJ MGP_BALBcJ_G0029582
protein coding gene Chr5:68654097-68739230 (-)
C3H/HeJ MGP_C3HHeJ_G0029305
protein coding gene Chr5:70508702-70595684 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030036
protein coding gene Chr5:73550687-73663526 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027276
protein coding gene Chr5:63787180-63863506 (-)
CAST/EiJ MGP_CASTEiJ_G0028713
protein coding gene Chr5:69646921-69741665 (-)
CBA/J MGP_CBAJ_G0029274
protein coding gene Chr5:75905789-76009423 (-)
DBA/2J MGP_DBA2J_G0029420
protein coding gene Chr5:68031328-68120002 (-)
FVB/NJ MGP_FVBNJ_G0029380
protein coding gene Chr5:67212691-67299646 (-)
LP/J MGP_LPJ_G0029505
protein coding gene Chr5:71080942-71171408 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029408
protein coding gene Chr5:79113323-79229382 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030069
protein coding gene Chr5:69738941-69828666 (-)
PWK/PhJ MGP_PWKPhJ_G0028437
protein coding gene Chr5:67015351-67100460 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028271
protein coding gene Chr5:69111248-69200035 (-)
WSB/EiJ MGP_WSBEiJ_G0028793
protein coding gene Chr5:69988216-70079048 (-)



Homology
more
  • Human Ortholog
    GABRG1, gamma-aminobutyric acid type A receptor gamma1 subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GABRG1, gamma-aminobutyric acid type A receptor gamma1 subunit
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2565
    neXtProt AC: NX_Q8N1C3
    UniProt: Q8N1C3

  • Chr Location
    4p12; chr4:46035769-46124065 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14405 NCBI Gene Model | MGI Sequence Detail 91571 C57BL/6J ±  kb
transcript NM_010252 RefSeq | MGI Sequence Detail 4771 C57BL/6  
polypeptide Q9R0Y8 UniProt | EBI | MGI Sequence Detail 465 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000007777 gamma-aminobutyric acid receptor subunit gamma-1
  • InterPro Domains
    IPR005438 Gamma-aminobutyric-acid A receptor, gamma 1 subunit
    IPR005437 Gamma-aminobutyric-acid A receptor, gamma subunit
    IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
    IPR006201 Neurotransmitter-gated ion-channel
    IPR018000 Neurotransmitter-gated ion-channel, conserved site
    IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
    IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily
    IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
    IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily
Molecular
Reagents
less
  • All nucleic 38
    Genomic 10
    cDNA 25
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-24022
References
more
  • Summaries
    All 64
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 18
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:238190 Alldred MJ, et al., Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice. J Comp Neurol. 2015 Jan 01;523(1):61-74

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory