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Barx1
Gene Detail
Symbol

Name
ID
Barx1
BarH-like homeobox 1
MGI:103124
Feature Type
protein coding gene
Genetic Map
Chromosome 13
24.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:48662998-48666507 bp, + strand
From VEGA annotation of GRCm38

  3510 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7241  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Barx1

Human
homologs
Human Homolog BARX1, BARX homeobox 1
NCBI Gene ID 56033
neXtProt AC  NX_Q9HBU1
Human Chr (Location)  9q12; chr9:93951627-93955326 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation die around E13 embryonic stage with shrunken and malformed stomach or shortly after birth with cleft palate and abnormal tooth development depending on strain background.
 
Interactions
Barx1 interacts with 51 markers (Mir17, Mir20b, Mir28b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process anatomical structure development, anterior/posterior pattern specification, ...
Component nucleus
Function DNA binding, sequence-specific DNA binding
External Resources: FuncBase
Expression
Literature Summary: (64 records)
Data Summary: Results (224)    Tissues (143)    Images (54)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 163
Northern blot 26
Western blot 6
RT-PCR 29
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(1) cDNA(17) Primer pair(3) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037223 (Evidence)
Ensembl Gene ModelENSMUSG00000021381 (Evidence)
Entrez Gene12022 (Evidence)
UniGene42241
DFCITC1586646
DoTSDT.40153392
NIA Mouse Gene IndexU014813
Consensus CDS ProjectCCDS49258.1
International Mouse Knockout Project StatusBarx1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037223 VEGA Gene Model | MGI Sequence Detail 3510 C57BL/6J ±  kb
transcript OTTMUST00000095992 VEGA | MGI Sequence Detail 1399 Not Applicable 
polypeptide OTTMUSP00000053586 VEGA | MGI Sequence Detail 254 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(1 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000047 Helix-turn-helix motif
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000004645 homeobox protein BarH-like 1
References
(Earliest) J:26186 Tissier-Seta JP, et al., Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev. 1995 May;51(1):3-15
(Latest) J:214666 Brunskill EW, et al., A gene expression atlas of early craniofacial development. Dev Biol. 2014 Jul 15;391(2):133-46
All references(88)
Other
accession IDs
MGD-MRK-23988

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory