Barx1
Gene Detail

Symbol Name ID

Barx1 BarH-like homeobox 1 MGI:103124

Feature Type

protein coding gene

Genetic Map

Chromosome 13

24.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr13:48662998-48666507 bp, + strand From VEGA annotation of GRCm38   3510 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7241  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Barx1

Human homologs

Human Homolog		BARX1, BARX homeobox 1
NCBI Gene ID		56033
neXtProt AC		NX_Q9HBU1
Human Chr (Location)		9q12; chr9:96713909-96717608 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a null mutation die around E13 embryonic stage with shrunken and malformed stomach or shortly after birth with cleft palate and abnormal tooth development depending on strain background.

 

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	anatomical structure development, anterior/posterior pattern specification, ...
Component	nucleus
Function	DNA binding, sequence-specific DNA binding, ...

External Resources: FuncBase

Expression

Literature Summary: (58 records)
Data Summary: Results (210)    Tissues (140)    Images (27)
Theiler Stages: 8, 9, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 28

Assay Type	Results
RNA in situ	163
Northern blot	26
RT-PCR	21

cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) Genomic(1) cDNA(17) Primer pair(2) Other(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000037223 (Evidence)
Ensembl Gene Model	ENSMUSG00000021381 (Evidence)
Entrez Gene	12022 (Evidence)
UniGene	42241
DFCI	TC1586646
DoTS	DT.40153392
NIA Mouse Gene Index	U014813
Consensus CDS Project	CCDS49258.1
International Mouse Knockout Project Status	Barx1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000037223	VEGA Gene Model | MGI Sequence Detail	3510	C57BL/6J
transcript	OTTMUST00000095992	VEGA | MGI Sequence Detail	1399	Not Applicable
polypeptide	OTTMUSP00000053586	VEGA | MGI Sequence Detail	254	Not Applicable

All sequences(20) RefSeq(2) UniProt(1)

Protein-related information

Resource	ID	Description
InterPro	IPR000047	Helix-turn-helix motif
InterPro	IPR017970	Homeobox, conserved site
InterPro	IPR001356	Homeodomain
InterPro	IPR009057	Homeodomain-like
InterPro	IPR020479	Homeodomain, metazoa
Protein Ontology	PR:000004645	homeobox protein BarH-like 1

References

(Earliest) J:26186 Tissier-Seta JP, et al., Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev. 1995 May;51(1):3-15
(Latest) J:187966 Jeong J, et al., Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate. Dev Dyn. 2012 Nov;241(11):1757-69
All references(82)

Other accession IDs

MGD-MRK-23988