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Anapc1 Gene Detail
Summary
  • Symbol
    Anapc1
  • Name
    anaphase promoting complex subunit 1
  • Synonyms
    2610021O03Rik, Apc1, Mcpr, tsg24
  • Feature Type
    protein coding gene
  • IDs
    MGI:103097
    NCBI Gene: 17222
  • Gene Overview
    MyGene.info: ANAPC1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:128610104-128687391 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 62.63 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    641 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103097
protein coding gene Chr2:128610083-128687395 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026474
protein coding gene Chr2:131954513-132040419 (-)
A/J MGP_AJ_G0026438
protein coding gene Chr2:126612162-126691091 (-)
AKR/J MGP_AKRJ_G0026413
protein coding gene Chr2:130210308-130288529 (-)
BALB/cJ MGP_BALBcJ_G0026450
protein coding gene Chr2:126875652-126953357 (-)
C3H/HeJ MGP_C3HHeJ_G0026193
protein coding gene Chr2:130717975-130801055 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026895
protein coding gene Chr2:136079373-136160574 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024272
protein coding gene Chr2:121437409-121517545 (-)
CAST/EiJ MGP_CASTEiJ_G0025654
protein coding gene Chr2:130953525-131038247 (-)
CBA/J MGP_CBAJ_G0026173
protein coding gene Chr2:141101137-141185408 (-)
DBA/2J MGP_DBA2J_G0026307
protein coding gene Chr2:126003756-126080307 (-)
FVB/NJ MGP_FVBNJ_G0026271
protein coding gene Chr2:124652250-124729450 (-)
LP/J MGP_LPJ_G0026412
protein coding gene Chr2:132185304-132264179 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026291
protein coding gene Chr2:145058054-145135942 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026950
protein coding gene Chr2:130239280-130319340 (-)
PWK/PhJ MGP_PWKPhJ_G0025390
protein coding gene Chr2:125576770-125653900 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025192
protein coding gene Chr2:129350199-129427334 (-)
WSB/EiJ MGP_WSBEiJ_G0025728
protein coding gene Chr2:131152476-131230805 (-)



Homology
more
  • Human Ortholog
    ANAPC1, anaphase promoting complex subunit 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ANAPC1, anaphase promoting complex subunit 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APC1, MCPR, TSG24
  • Links
    NCBI Gene ID: 64682
    neXtProt AC: NX_Q9H1A4
    UniProt: Q9H1A4

  • Chr Location
    2q13; chr2:111766147-111884196 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000014355 Ensembl Gene Model | MGI Sequence Detail 77288 C57BL/6J ±  kb
transcript ENSMUST00000014499 Ensembl | MGI Sequence Detail 8942 Not Applicable  
polypeptide ENSMUSP00000014499 Ensembl | MGI Sequence Detail 1944 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-23961, MGI:1923795, MGI:2138834, MGI:2139095, MGI:2139376
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:239017 Steinmetz CC, et al., Upregulation of mu3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Cell Rep. 2016 Sep 06;16(10):2711-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory