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Stx3 Gene Detail
Summary
  • Symbol
    Stx3
  • Name
    syntaxin 3
  • Synonyms
    Syn-3, syntaxin 3A, syntaxin 3B
  • Feature Type
    protein coding gene
  • IDs
    MGI:103077
    NCBI Gene: 20908
  • Gene Overview
    MyGene.info: STX3
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:11775118-11819403 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 8.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    391 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103077
protein coding gene Chr19:11775118-11819886 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024886
protein coding gene Chr19:9165095-9211548 (-)
A/J MGP_AJ_G0024860
protein coding gene Chr19:8652370-8697825 (-)
AKR/J MGP_AKRJ_G0024835
protein coding gene Chr19:8976917-9031576 (-)
BALB/cJ MGP_BALBcJ_G0024860
protein coding gene Chr19:8653740-8698314 (-)
C3H/HeJ MGP_C3HHeJ_G0024626
protein coding gene Chr19:8876808-8925111 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025308
protein coding gene Chr19:9615491-9666393 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022734
protein coding gene Chr19:9239140-9282733 (-)
CAST/EiJ MGP_CASTEiJ_G0024099
protein coding gene Chr19:8469697-8528198 (-)
CBA/J MGP_CBAJ_G0024600
protein coding gene Chr19:9682464-9730947 (-)
DBA/2J MGP_DBA2J_G0024727
protein coding gene Chr19:8615440-8661602 (-)
FVB/NJ MGP_FVBNJ_G0024694
protein coding gene Chr19:8647280-8690570 (-)
LP/J MGP_LPJ_G0024814
protein coding gene Chr19:9167005-9218540 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024721
protein coding gene Chr19:9593012-9644966 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025356
protein coding gene Chr19:8961252-9009724 (-)
PWK/PhJ MGP_PWKPhJ_G0023843
protein coding gene Chr19:8083074-8126809 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023649
protein coding gene Chr19:8135542-8187701 (-)
WSB/EiJ MGP_WSBEiJ_G0024161
protein coding gene Chr19:8811361-8863149 (-)



Homology
more
  • Human Ortholog
    STX3, syntaxin 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STX3, syntaxin 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    STX3A
  • Links
    NCBI Gene ID: 6809
    neXtProt AC: NX_Q13277
    UniProt: Q13277

  • Chr Location
    11q12.1; chr11:59755059-59805882 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 80191
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: STX3
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041488 Ensembl Gene Model | MGI Sequence Detail 44286 C57BL/6J ±  kb
    transcript ENSMUST00000069285 Ensembl | MGI Sequence Detail 2810 Not Applicable  
    polypeptide ENSMUSP00000069529 Ensembl | MGI Sequence Detail 289 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 28
      Primer pair 6

      Microarray probesets 11
    Other
    Accession IDs
    less
    MGD-MRK-23941, MGI:2147464, MGI:2147666, MGI:2147735
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 12
      Gene Ontology 16
      Phenotypes 6
    • Earliest
      J:26509 Ibaraki K, et al., Identification of four different forms of syntaxin 3. Biochem Biophys Res Commun. 1995 Jun 26;211(3):997-1005
    • Latest
      J:240239 Weis VG, et al., Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. Cell Mol Gastroenterol Hepatol. 2016 Feb 01;2(2):131-157

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/27/2018
    MGI 6.13
    The Jackson Laboratory