About   Help   FAQ
Stx3
Gene Detail
Symbol

Name
ID
Stx3
syntaxin 3
MGI:103077
Synonyms
Syn-3, syntaxin 3A, syntaxin 3B
Feature Type
protein coding gene
Genetic Map
Chromosome 19
8.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:11775119-11819403 bp, - strand
From Ensembl annotation of GRCm38

  44285 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:80191  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STX3
Protein SuperFamily: syntaxin
Gene Tree: Stx3

Human
homologs
STX3, syntaxin 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6809
neXtProt AC: NX_Q13277

Human Synonyms: STX3A

Human Chr (Location): 11q12.1; chr11:59755059-59805882 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(8) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Stx3 interacts with 270 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (43 annotations)
Process exocytosis, intracellular protein transport, ...
Component apical plasma membrane, azurophil granule, ...
Function arachidonic acid binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (46)    Tissues (33)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 42
RT-PCR 4
cDNA source data(23)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase stx3    NEW 
Molecular
reagents
All nucleic(27) cDNA(25) Primer pair(2)
Microarray probesets(11)
Other database
links
Ensembl Gene Model ENSMUSG00000041488 (Evidence)
Entrez Gene 20908 (Evidence)
DFCI TC1605600, TC1592990, TC1592377, TC1579230, TC1649844, TC1635715, TC1630740
NIA Mouse Gene Index U038835
Consensus CDS Project CCDS29611.1, CCDS29612.1, CCDS29613.1
International Mouse Phenotyping Consortium Status Stx3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041488 Ensembl Gene Model | MGI Sequence Detail 44285 C57BL/6J ±  kb
transcript ENSMUST00000069285 Ensembl | MGI Sequence Detail 3269 Not Applicable 
polypeptide ENSMUSP00000069529 Ensembl | MGI Sequence Detail 289 Not Applicable 

For the selected sequences
All sequences(72) RefSeq(19) UniProt(5)
Polymorphisms
SNPs within 2kb(392 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006012 Syntaxin/epimorphin, conserved site
InterPro IPR006011 Syntaxin, N-terminal
InterPro IPR000727 Target SNARE coiled-coil domain
InterPro IPR010989 t-SNARE
Protein Ontology PR:000015795 syntaxin-3
References
(Earliest) J:26509 Ibaraki K, et al., Identification of four different forms of syntaxin 3. Biochem Biophys Res Commun. 1995 Jun 26;211(3):997-1005
(Latest) J:200047 Yatsu A, et al., Syntaxin-3 is required for melanosomal localization of tyrp1 in melanocytes. J Invest Dermatol. 2013 Sep;133(9):2237-46
All references(45)
Other
accession IDs
MGD-MRK-23941, MGI:2147464, MGI:2147666, MGI:2147735

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory