Stx3
Gene Detail

Symbol Name ID

Stx3 syntaxin 3 MGI:103077

Synonyms

Syn-3, syntaxin 3A, syntaxin 3B

Feature Type

protein coding gene

Genetic Map

Chromosome 19

8.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:11775119-11819403 bp, - strand From Ensembl annotation of GRCm38   44285 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:80191  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: syntaxin
Gene Tree: Stx3

Human homologs

Human Homolog		STX3, syntaxin 3
NCBI Gene ID		6809
neXtProt AC		NX_Q13277
Human Synonyms		STX3A
Human Chr (Location)		11q12.1; chr11:59522532-59573355 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(9) : Targeted(1) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (27 annotations)

Process	cellular membrane fusion, cellular response to oxidative stress, ...
Component	apical plasma membrane, azurophil granule, ...
Function	arachidonic acid binding, protein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (8 records)
Data Summary: Results (42)    Tissues (33)    Images (18)
Theiler Stages: 19, 23, 24, 28

Assay Type	Results
RNA in situ	42

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(24)
Microarray probesets(11)

Other database links

Ensembl Gene Model	ENSMUSG00000041488 (Evidence)
Entrez Gene	20908 (Evidence)
DFCI	TC1579230, TC1592377, TC1592990, TC1605600, TC1630740, TC1635715, TC1649844
NIA Mouse Gene Index	U038835
Consensus CDS Project	CCDS29611.1, CCDS29612.1, CCDS29613.1
International Mouse Knockout Project Status	Stx3

Sequences

Length	Strain/Species
genomic	ENSMUSG00000041488	Ensembl Gene Model | MGI Sequence Detail	44285	C57BL/6J
transcript	ENSMUST00000069285	Ensembl | MGI Sequence Detail	3269	Not Applicable
polypeptide	ENSMUSP00000069529	Ensembl | MGI Sequence Detail	289	Not Applicable

All sequences(57) RefSeq(7) UniProt(5)

Polymorphisms

SNPs(329 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015708	Syntaxin-3
InterPro	IPR006012	Syntaxin/epimorphin, conserved site
InterPro	IPR006011	Syntaxin, N-terminal
InterPro	IPR000727	Target SNARE coiled-coil domain
InterPro	IPR010989	t-SNARE
Protein Ontology	PR:000015795	syntaxin-3

References

(Earliest) J:26509 Ibaraki K, et al., Identification of four different forms of syntaxin 3. Biochem Biophys Res Commun. 1995 Jun 26;211(3):997-1005
(Latest) J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
All references(43)

Other accession IDs

MGD-MRK-23941, MGI:2147464, MGI:2147666, MGI:2147735