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Ecm1
Gene Detail
 Symbol
Name
ID
Ecm1
extracellular matrix protein 1
MGI:103060
Synonyms p85
Feature Type protein coding gene
Genetic Map
Chromosome 3
40.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr3:95734147-95739569 bp, - strand
From VEGA annotation of GRCm38

  5423 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3260  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Ecm1

Human
homologs
Human Homolog ECM1, extracellular matrix protein 1
NCBI Gene ID 1893
neXtProt AC  NX_Q16610
Human Synonyms  URBWD
Human Chr (Location)  1q21; chr1:150508011-150513789 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ECM1
Alleles
and
phenotypes
All alleles(7) : Targeted(4) Gene trapped(3)
 
Mice homozygous for a knock-out allele exhibit auto-inflammatory disease and do not survive beyond 6 to 8 weeks of age.
 
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process angiogenesis, biomineral tissue development, ...
Component extracellular matrix, extracellular region, ...
Function enzyme binding, interleukin-2 receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (20)    Tissues (10)    Images (2)
Theiler Stages: 23, 24, 26
Assay TypeResults
Immunohistochemistry 1
Northern blot 14
RT-PCR 5
cDNA source data(113)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(116) cDNA(113) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000030311 (Evidence)
Ensembl Gene ModelENSMUSG00000028108 (Evidence)
Entrez Gene13601 (Evidence)
UniGene3433
DFCITC1574159
DoTSDT.494671
NIA Mouse Gene IndexU024368
Consensus CDS ProjectCCDS17619.1, CCDS57237.1
International Mouse Knockout Project StatusEcm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030311 VEGA Gene Model | MGI Sequence Detail 5423 C57BL/6J ±  kb
transcript OTTMUST00000075058 VEGA | MGI Sequence Detail 1900 Not Applicable 
polypeptide OTTMUSP00000039277 VEGA | MGI Sequence Detail 559 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(12) UniProt(11)
Polymorphisms RFLP(2) : SNPs within 2kb(76 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008605 Extracellular matrix 1
InterPro IPR020858 Serum albumin-like
Protein Ontology PR:000006879 extracellular matrix protein 1
References (Earliest) J:26941 Capeless CG, et al., Hydrolysis of sucrose octa-acetate: qualitative differences in taster and demistaster avoidance phenotypes. Chem Senses. 1994 Dec;19(6):595-607
(Latest) J:168252 Li Z, et al., ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol. 2011 Feb;12(2):178-85
All references(42)
Other
accession IDs
MGD-MRK-23922, MGI:2139781

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory