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Rsu1 Gene Detail
Summary
  • Symbol
    Rsu1
  • Name
    Ras suppressor protein 1
  • Synonyms
    rsp-1, RsuI
  • Feature Type
    protein coding gene
  • IDs
    MGI:103040
    NCBI Gene: 20163
  • Gene Overview
    MyGene.info: RSU1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:13076967-13271416 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 9.73 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1008 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103040
protein coding gene Chr2:13076821-13271416 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025354
protein coding gene Chr2:10554327-10758154 (-)
A/J MGP_AJ_G0025331
protein coding gene Chr2:10163893-10357625 (-)
AKR/J MGP_AKRJ_G0025300
protein coding gene Chr2:10455176-10657196 (-)
BALB/cJ MGP_BALBcJ_G0025327
protein coding gene Chr2:10150872-10348229 (-)
C3H/HeJ MGP_C3HHeJ_G0025087
protein coding gene Chr2:10399376-10605452 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025769
protein coding gene Chr2:10837237-11042419 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023184
protein coding gene Chr2:9771716-9960425 (-)
CAST/EiJ MGP_CASTEiJ_G0024550
protein coding gene Chr2:10373100-10570550 (-)
CBA/J MGP_CBAJ_G0025066
protein coding gene Chr2:11322574-11522642 (-)
DBA/2J MGP_DBA2J_G0025198
protein coding gene Chr2:10059617-10252555 (-)
FVB/NJ MGP_FVBNJ_G0025160
protein coding gene Chr2:9954798-10148208 (-)
LP/J MGP_LPJ_G0025284
protein coding gene Chr2:10461512-10666868 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025192
protein coding gene Chr2:11196346-11399248 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025827
protein coding gene Chr2:10374110-10573437 (-)
PWK/PhJ MGP_PWKPhJ_G0024301
protein coding gene Chr2:9952094-10139802 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024101
protein coding gene Chr2:10411366-10606502 (-)
WSB/EiJ MGP_WSBEiJ_G0024620
protein coding gene Chr2:10460564-10665687 (-)



Homology
more
  • Human Ortholog
    RSU1, Ras suppressor protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RSU1, Ras suppressor protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RSP-1
  • Links
    NCBI Gene ID: 6251
    neXtProt AC: NX_Q15404
    UniProt: Q15404

  • Chr Location
    10p13; chr10:16590616-16817537 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7521
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: RSU1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20163 NCBI Gene Model | MGI Sequence Detail 194450 C57BL/6J ±  kb
transcript NM_009105 RefSeq | MGI Sequence Detail 1607 C57BL/6-cast*  
polypeptide Q01730 UniProt | EBI | MGI Sequence Detail 277 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    9 Sequences
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
less
  • All nucleic 124
    cDNA 123
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-23902
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:43405 Cutler ML, et al., Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformation. Mol Cell Biol. 1992 Sep;12(9):3750-6
  • Latest
    J:208112 Porcheri C, et al., Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain. J Neurosci. 2014 Apr 9;34(15):5222-32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory