About   Help   FAQ
Inmt Gene Detail
Summary
  • Symbol
    Inmt
  • Name
    indolethylamine N-methyltransferase
  • Synonyms
    Temt
  • Feature Type
    protein coding gene
  • IDs
    MGI:102963
    NCBI Gene: 21743
Location & Maps
more
  • Sequence Map
    Chr6:55170626-55175043 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4418 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 27.38 cM, cytoband B3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    INMT, indolethylamine N-methyltransferase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    INMT, indolethylamine N-methyltransferase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TEMT
  • Links
    NCBI Gene ID: 11185
    neXtProt AC: NX_O95050

  • Chr Location
    7p14.3; chr7:30752135-30757602 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026997 VEGA Gene Model | MGI Sequence Detail 4418 C57BL/6J ±  kb
transcript OTTMUST00000066722 VEGA | MGI Sequence Detail 1077 Not Applicable  
polypeptide OTTMUSP00000033481 VEGA | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009039 indolethylamine N-methyltransferase
  • EC
  • InterPro Domains
    IPR000940 Methyltransferase, NNMT/PNMT/TEMT
    IPR025820 Methyltransferase NNMT/PNMT/TEMT, conserved site
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 136
    cDNA 136

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-23800
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:26180 Mozier NM, et al., S-adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme in sulfur and selenium metabolism. J Biol Chem. 1988 Apr 5;263(10):4527-31
  • Latest
    J:222440 Huang J, et al., Bmp4 from the optic vesicle specifies murine retina formation. Dev Biol. 2015 Jun 1;402(1):119-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory