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Rpl5
Gene Detail
Symbol

Name
ID
Rpl5
ribosomal protein L5
MGI:102854
Synonyms
U21RNA
Feature Type
protein coding gene
Genetic Map
Chromosome 5
52.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:107900502-107909005 bp, + strand
From VEGA annotation of GRCm38

  8504 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110649  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: ribosomal protein L5/L18p
Gene Tree: Rpl5

Human
homologs
Human Homolog RPL5, ribosomal protein L5
NCBI Gene ID 6125
neXtProt AC  NX_P46777
Human Synonyms  DBA6, L5, PPP1R135
Human Chr (Location)  1p22.1; chr1:92832037-92841924 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RPL5
Mutations,
alleles, and
phenotypes
All mutations/alleles(33) : Gene trapped(33)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rpl5 interacts with 135 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (41)    Tissues (34)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
Northern blot 19
RT-PCR 2
cDNA source data(16)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(1) cDNA(16) Primer pair(2) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000028907 (Evidence)
Ensembl Gene ModelENSMUSG00000058558 (Evidence)
Entrez Gene100503670 (Evidence)
Consensus CDS ProjectCCDS39199.1
International Mouse Knockout Project StatusRpl5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028907 VEGA Gene Model | MGI Sequence Detail 8504 C57BL/6J ±  kb
transcript OTTMUST00000071641 VEGA | MGI Sequence Detail 2045 Not Applicable 
polypeptide OTTMUSP00000036755 VEGA | MGI Sequence Detail 297 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(4) UniProt(11)
Polymorphisms
SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005484 Ribosomal protein L18/L5
InterPro IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal
InterPro IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal
Protein Ontology PR:000014230 60S ribosomal protein L5
References
(Earliest) J:18668 Rudert F, et al., Cloning a pseudogene and cDNA encoding a 17-kDa ribosomal protein from mouse: structure and regulation of expression. Gene. 1993 Nov 15;133(2):249-54
(Latest) J:187617 Bywater MJ, et al., Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53. Cancer Cell. 2012 Jul 10;22(1):51-65
All references(41)
Other
accession IDs
MGD-MRK-23687

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory