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Lmo3 Gene Detail
Summary
  • Symbol
    Lmo3
  • Name
    LIM domain only 3
  • Synonyms
    Rbtn3, Rbtn-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102810
    NCBI Gene: 109593
  • Gene Overview
    MyGene.info: LMO3
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:138362918-138581968 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 69.02 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2486 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102810
protein coding gene Chr6:138362918-138581968 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031441
protein coding gene Chr6:142935900-143181213 (-)
A/J MGP_AJ_G0031416
protein coding gene Chr6:137318253-137536654 (-)
AKR/J MGP_AKRJ_G0031344
protein coding gene Chr6:141489831-141716922 (-)
BALB/cJ MGP_BALBcJ_G0031423
protein coding gene Chr6:137167188-137390719 (-)
C3H/HeJ MGP_C3HHeJ_G0031145
protein coding gene Chr6:141513354-141743257 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031885
protein coding gene Chr6:146831666-147074060 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029014
protein coding gene Chr6:136320353-136536017 (-)
CAST/EiJ MGP_CASTEiJ_G0030513
protein coding gene Chr6:141005329-141245784 (-)
CBA/J MGP_CBAJ_G0031105
protein coding gene Chr6:152433696-152700082 (-)
DBA/2J MGP_DBA2J_G0031262
protein coding gene Chr6:136169341-136401228 (-)
FVB/NJ MGP_FVBNJ_G0031213
protein coding gene Chr6:135020710-135240725 (-)
LP/J MGP_LPJ_G0031346
protein coding gene Chr6:143073093-143310615 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031253
protein coding gene Chr6:156226705-156489495 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031917
protein coding gene Chr6:141227939-141457540 (-)
PWK/PhJ MGP_PWKPhJ_G0030240
protein coding gene Chr6:134647173-134872031 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030064
protein coding gene Chr6:139478861-139710068 (-)
WSB/EiJ MGP_WSBEiJ_G0030606
protein coding gene Chr6:141864071-142111438 (-)



Homology
more
  • Human Ortholog
    LMO3, LIM domain only 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    LMO3, LIM domain only 3
    Orthology source: HGNC
  • Synonyms
    RBTN3, RBTNL2, Rhom-3, RHOM3
  • Links
    NCBI Gene ID: 55885
    neXtProt AC: NX_Q8TAP4
    UniProt: Q8TAP4

  • Chr Location
    12p12.3; chr12:16548372-16610233 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    1 phenotype from multigenic genotypes
    3 phenotype references
Homozygous mutant mice show no overt phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 109593 NCBI Gene Model | MGI Sequence Detail 219051 C57BL/6J ±  kb
transcript NR_151449 RefSeq | MGI Sequence Detail 4206 C57BL/6  
polypeptide Q8BZL8 UniProt | EBI | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR001781 Zinc finger, LIM-type
Molecular
Reagents
less
  • All nucleic 18
    Genomic 2
    cDNA 12
    Other 4

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-13798, MGD-MRK-13801, MGD-MRK-19718, MGI:2141511, MGI:2141726
References
more
  • Summaries
    All 62
    Developmental Gene Expression 40
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:2046 Foroni L, et al., The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. J Mol Biol. 1992 Aug 5;226(3):747-61
  • Latest
    J:254118 De Clercq S, et al., DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation. Cereb Cortex. 2018 Feb 1;28(2):493-509

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory