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Rab20
Gene Detail
Symbol

Name
ID
Rab20
RAB20, member RAS oncogene family
MGI:102789
Synonyms
D8Ertd350e
Feature Type
protein coding gene
Genetic Map
Chromosome 8
5.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:11453513-11478499 bp, - strand
From NCBI annotation of GRCm38

  24987 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9856  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB20
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab20

Human
homologs
RAB20, RAB20, member RAS oncogene family
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 55647
neXtProt AC: NX_Q9NX57

Human Chr (Location): 13q34; chr13:110523066-110561737 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab20 interacts with 110 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process intracellular protein transport, phagosome acidification, ...
Component cytoplasmic vesicle, early endosome, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (4)    Tissues (4)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 3
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab20    NEW 
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000031504 (Evidence)
Entrez Gene 19332 (Evidence)
DFCI TC1581612
DoTS DT.496913
Consensus CDS Project CCDS22095.1
International Mouse Phenotyping Consortium Status Rab20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19332 NCBI Gene Model | MGI Sequence Detail 24987 C57BL/6J ±  kb
transcript NM_011227 RefSeq | MGI Sequence Detail 722 Not Specified 
polypeptide P35295 UniProt | EBI | MGI Sequence Detail 233 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(4)
Polymorphisms
RFLP(2) : SNPs within 2kb(294 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013593 ras-related protein Rab-20
Graphical View of Protein Domain Structure
References
(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:218419 Segawa T, et al., Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20. Biochem J. 2014 Dec 15;464(3):365-75
All references(37)
Other
accession IDs
MGD-MRK-19697, MGI:1196323, MGI:2142428

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory