About   Help   FAQ
Rab20
Gene Detail
Symbol

Name
ID
Rab20
RAB20, member RAS oncogene family
MGI:102789
Synonyms
D8Ertd350e
Feature Type
protein coding gene
Genetic Map
Chromosome 8
5.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:11453977-11478499 bp, - strand
From NCBI annotation of GRCm38

  24523 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9856  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab20

Human
homologs
Human Homolog RAB20, RAB20, member RAS oncogene family
NCBI Gene ID 55647
neXtProt AC  NX_Q9NX57
Human Chr (Location)  13q34; chr13:110523066-110561724 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab20 interacts with 111 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process GTP catabolic process, intracellular protein transport, ...
Component cytoplasmic vesicle, early endosome, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (4)    Tissues (4)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 3
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031504 (Evidence)
Entrez Gene19332 (Evidence)
DFCITC1581612
DoTSDT.496913
Consensus CDS ProjectCCDS22095.1
International Mouse Knockout Project StatusRab20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19332 NCBI Gene Model | MGI Sequence Detail 24523 C57BL/6J ±  kb
transcript NM_011227 RefSeq | MGI Sequence Detail 722 Not Specified 
polypeptide P35295 UniProt | EBI | MGI Sequence Detail 233 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(7)
Polymorphisms
RFLP(2) : SNPs within 2kb(292 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013593 ras-related protein Rab-20
Graphical View of Protein Domain Structure
References
(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:170282 Hackenbeck T, et al., The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia. Biochim Biophys Acta. 2011 Jan;1813(1):1-13
All references(38)
Other
accession IDs
MGD-MRK-19697, MGI:1196323, MGI:2142428

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory