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Rab20
Gene Detail
 Symbol
Name
ID
Rab20
RAB20, member RAS oncogene family
MGI:102789
Synonyms D8Ertd350e
Feature Type protein coding gene
Genetic Map
Chromosome 8
5.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:11453977-11478499 bp, - strand
From NCBI annotation of GRCm38

  24523 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
HomoloGene:9856  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab20

Human
homologs
Human Homolog RAB20, RAB20, member RAS oncogene family
NCBI Gene ID 55647
neXtProt AC  NX_Q9NX57
Human Chr (Location)  13q34; chr13:110523066-110561724 (-)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process phagosome acidification, phagosome-lysosome fusion, ...
Component cytoplasmic vesicle, Golgi apparatus, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (4)    Tissues (3)    Images (1)
Theiler Stages: 13, 26, 28
Assay TypeResults
RNA in situ 1
RT-PCR 3
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031504 (Evidence)
Entrez Gene19332 (Evidence)
DFCITC1581612
DoTSDT.496913
Consensus CDS ProjectCCDS22095.1
International Mouse Knockout Project StatusRab20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19332 NCBI Gene Model | MGI Sequence Detail 24523 C57BL/6J ±  kb
transcript NM_011227 RefSeq | MGI Sequence Detail 722 Not Specified 
polypeptide P35295 UniProt | EBI | MGI Sequence Detail 233 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(292 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013593 ras-related protein Rab-20
Graphical View of Protein Domain Structure
References (Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:170282 Hackenbeck T, et al., The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia. Biochim Biophys Acta. 2011 Jan;1813(1):1-13
All references(37)
Other
accession IDs
MGD-MRK-19697, MGI:1196323, MGI:2142428

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory