Rab20
Gene Detail

Symbol Name ID

Rab20 RAB20, member RAS oncogene family MGI:102789

Synonyms

D8Ertd350e

Feature Type

protein coding gene

Genetic Map

Chromosome 8

5.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:11453977-11478499 bp, - strand From NCBI annotation of GRCm38   24523 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9856  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab20

Human homologs

Human Homolog		RAB20, RAB20, member RAS oncogene family
NCBI Gene ID		55647
neXtProt AC		NX_Q9NX57
Human Chr (Location)		13q34; chr13:111175413-111214071 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	phagosome acidification, phagosome-lysosome fusion, ...
Component	Golgi apparatus, phagocytic vesicle
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (4)    Tissues (3)    Images (1)
Theiler Stages: 13, 26, 28

Assay Type	Results
RNA in situ	1
RT-PCR	3

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000031504 (Evidence)
Entrez Gene	19332 (Evidence)
DFCI	TC1581612
DoTS	DT.496913
Consensus CDS Project	CCDS22095.1
International Mouse Knockout Project Status	Rab20

Sequences

Length	Strain/Species
genomic	19332	NCBI Gene Model | MGI Sequence Detail	24523	C57BL/6J
transcript	NM_011227	RefSeq | MGI Sequence Detail	722	Not Specified
polypeptide	P35295	UniProt | EBI | MGI Sequence Detail	233	Not Applicable

All sequences(26) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(2) : SNPs(112 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013593	ras-related protein Rab-20

Graphical View of Protein Domain Structure

References

(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:170282 Hackenbeck T, et al., The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia. Biochim Biophys Acta. 2011 Jan;1813(1):1-13
All references(36)

Other accession IDs

MGD-MRK-19697, MGI:1196323, MGI:2142428