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Aimp1
Gene Detail
 Symbol
Name
ID
Aimp1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
MGI:102774
Synonyms 9830137A06Rik, AIMP1/p43, Emap2, EMAPII, Scye1
Feature Type protein coding gene
Genetic Map
Chromosome 3
61.48 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:132660498-132683879 bp, - strand
From NCBI annotation of GRCm38

  23382 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31260  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: endothelial monocyte-activating polypeptide II precursor (pro-EMAP II)
Gene Tree: Aimp1

Human
homologs
Human Homolog AIMP1, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
NCBI Gene ID 9255
neXtProt AC  NX_Q12904
Human Synonyms  EMAP2, EMAPII, HLD3, p43, SCYE1
Human Chr (Location)  4q24; chr4:106315610-106349225 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human AIMP1
Alleles
and
phenotypes
All alleles(39) : Gene trapped(33) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trap allele display delayed wound healing and decreased inflammatory response after wounding.
 
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process angiogenesis, apoptotic process, ...
Component aminoacyl-tRNA synthetase multienzyme complex, cell surface, ...
Function cytokine activity, protein homodimerization activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (169)    Tissues (114)    Images (21)
Theiler Stages: 13, 14, 18, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 8
RNA in situ 115
Western blot 46
cDNA source data(124)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(125) cDNA(124) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000028029 (Evidence)
Entrez Gene13722 (Evidence)
UniGene235137
DFCITC1574681, TC1598440
DoTSDT.101403857, DT.495538, DT.97337805
NIA Mouse Gene IndexU024664
Consensus CDS ProjectCCDS38642.1
International Mouse Knockout Project StatusAimp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13722 NCBI Gene Model | MGI Sequence Detail 23382 C57BL/6J ±  kb
transcript NM_007926 RefSeq | MGI Sequence Detail 1122 C57BL/6 
polypeptide P31230 UniProt | EBI | MGI Sequence Detail 310 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012340 Nucleic acid-binding, OB-fold
InterPro IPR002547 tRNA-binding domain
Protein Ontology PR:000014547 multisynthetase complex auxiliary component p43
Graphical View of Protein Domain Structure
References (Earliest) J:20657 Kao J, et al., Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II. J Biol Chem. 1994 Oct 7;269(40):25106-19
(Latest) J:184868 Hong HJ, et al., AIMP1 deficiency enhances airway hyperreactivity in mice via increased T(H)2 immune responses. Clin Immunol. 2012 Jun;143(3):256-65
All references(49)
Other
accession IDs
MGD-MRK-19681, MGI:2445109

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory