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Ces3a Gene Detail
Summary
  • Symbol
    Ces3a
  • Name
    carboxylesterase 3A
  • Synonyms
    Es31, Es-male carboxylesterase
  • Feature Type
    protein coding gene
  • IDs
    MGI:102773
    NCBI Gene: 382053
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105775233-105785045 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102773
 protein coding gene Chr8:105775208-105788560 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034025
 protein coding gene Chr8:107236749-107246529 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0033932
 protein coding gene Chr8:105963621-105992234 (+)
BALB/cJ MGP_BALBcJ_G0033999
 protein coding gene Chr8:103184576-103200679 (+)
C3H/HeJ MGP_C3HHeJ_G0033711
 protein coding gene Chr8:106718356-106730665 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034519
 protein coding gene Chr8:111182920-111196040 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017460
 protein coding gene Chr11:112768754-112779989 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0033839
 protein coding gene Chr8:102318195-102358837 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0033930
 protein coding gene Chr8:107450724-107472374 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033828
 protein coding gene Chr8:118014338-118023431 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034537
 protein coding gene Chr8:105945532-105957415 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0032579
 protein coding gene Chr8:104640468-104649761 (+)
WSB/EiJ MGP_WSBEiJ_G0033153
 protein coding gene Chr8:106600923-106617413 (+)



Homology
more
  • Human Ortholog
    CES3, carboxylesterase 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CES3, carboxylesterase 3
  • Synonyms
    ES31
  • Links
    NCBI Gene ID: 23491
    neXtProt AC: NX_Q6UWW8
    UniProt: Q6UWW8

  • Chr Location
    16q22.1; chr16:66961245-66975149 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    102
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069922 Ensembl Gene Model | MGI Sequence Detail 9813 C57BL/6J ±  kb
transcript ENSMUST00000093222 Ensembl | MGI Sequence Detail 2046 Not Applicable  
polypeptide ENSMUSP00000090910 Ensembl | MGI Sequence Detail 571 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 102
    cDNA 102

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-19680
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:13160 Aida K, et al., Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver. Biochim Biophys Acta. 1993 Jul 18;1174(1):72-4
  • Latest
    J:276211 Yang L, et al., A Unique Role of Carboxylesterase 3 (Ces3) in beta-Adrenergic Signaling-Stimulated Thermogenesis. Diabetes. 2019 Jun;68(6):1178-1196
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory